Jmjd3 is trimethyl H3K27 specific demethylase required for M2 macrophage polarization. Genomic fragments obtained from wild-type and Jmjd3-/- mouse macrophages were immunoprecipitated with anti H3K27me3 Ab, and deep sequencing was performed. wild-type and Jmjd3-/- macrophages
Proteomic analysis by mass spectrometry was performed to characterize proteins in ascites samples from patients with gastric cancer (N = 7) or liver cirrhosis (N = 3).
