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MetabolomicsMetabolic phenotyping of urine from a dementia research cohort
To better understand the molecular mechanisms underpinning physiological variation in human populations, metabolic phenotyping approaches are increasingly being applied to studies involving hundreds and thousands of biofluid samples. Hyphenated ultra-performance liquid chromatography-mass spectromet...
2022-03-01 | MTBLS719 | MetaboLights
ProteomicsQuantitative proteomics of cold adaptation of the Antarctic archaeon Halohasta litchfieldiae and Halorubrum lacusprofundi
Halohasta litchfieldiae and Halorubrum lacusprofundi are important members of Deep Lake in Antarctica, representing ~44% (the most abundance) and ~10% (the 3rd most abundance) of the lake population. Deep Lake is in the Vestfold Hills, East Antarctica (68°33’36.8S, 78°11’48.7E) and is 36 m deep, mon...
ORGANISM(S): Halohasta litchfieldiae Halorubrum lacusprofundi ATCC 49239 
2017-02-27 | PXD005076 | Pride
Antarctic microorganism  psychrophile  archaea  itraq  cold adaptation 
ProteomicsQuantitative proteomics of biofilm formation of the Antarctic archaeon Halorubrum lacusprofundi
Halorubrum lacusprofundi is an important member of Deep Lake in Antarctica, representing ~10% of the lake population (DeMaere et al., 2013). Deep Lake is in the Vestfold Hills, East Antarctica (68°33’36.8S, 78°11’48.7E) and is 36 m deep, monomictic, and perennially cold (down to -20°C) (DeMaere et a...
ORGANISM(S): Halorubrum lacusprofundi ATCC 49239 
2016-12-13 | PXD004202 | Pride
Antarctic microorganism  psychrophile  archaea  itraq 
UnknownA Single-Cell Roadmap of Lineage Bifurcation in Human ESC Models of Embryonic Brain Development.
Not available
S-EPMC5261831 | biostudies-literature
TranscriptomicsDevelopmental and metabolic plasticity of ripe Semillon grape berries in response to Botrytis cinerea during noble rot
Noble rot results from atypical infections of ripe grape berries by Botrytis cinerea. Unlike bunch rot, noble rot promotes favorable changes in grape berries and accumulation of secondary metabolites that enhance wine grape quality. Noble rot-infected berries of Sémillon, a white-skinned variety, w...
ORGANISM(S): Vitis vinifera 
2015-10-12 | E-GEOD-67932 | biostudies-arrayexpress
TranscriptomicsTranscriptional effects of CTGF inhibition in a transgenic mouse model of dilated cardiomyopathy
Cardiac structural changes associated with dilated cardiomyopathy (DCM) include cardiomyocyte hypertrophy and myocardial fibrosis. Connective Tissue Growth Factor (CTGF) has been associated with tissue remodeling and is highly expressed in failing hearts. To test if inhibition of CTGF would alter ...
ORGANISM(S): Mus musculus 
2015-11-20 | E-GEOD-68857 | biostudies-arrayexpress
UnknownHCN2 Rescues brain defects by enforcing endogenous voltage pre-patterns.
Not available
S-EPMC5843655 | biostudies-literature
UnknownCortical circuit-based lossless neural integrator for perceptual decision-making: A computational modeling study.
Not available
S-EPMC9669970 | biostudies-literature
UnknownCoordinating heart morphogenesis: A novel role for hyperpolarization-activated cyclic nucleotide-gated (HCN) channels during cardiogenesis in Xenopus laevis.
Not available
S-EPMC5501196 | biostudies-literature
UnknownThe Causal Effects of Blood Iron and Copper on Lipid Metabolism Diseases: Evidence from Phenome-Wide Mendelian Randomization Study.
Not available
S-EPMC7603077 | biostudies-literature
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