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TranscriptomicsIllumina Sentrix 6 mouse BeadChip gene expression analysis in mouse spinal cord in the EAE model of Multiple Sclerosis
The study assessed the efficacy of R-flurbiprofen in experimental autoimmune encephalomyelitis (EAE) models of multiple sclerosis in mice. R-flurbiprofen, also known as tarenflurbil, is the R-enantiomer of the cyclooxyygenase inhibitor S-flurbiprofen. It is ineffective in terms of cyclooxygenase inh...
ORGANISM(S): Mus musculus 
2014-08-28 | E-GEOD-60847 | biostudies-arrayexpress
UnknownShort leukocyte telomere length is associated with obesity in American Indians: the Strong Heart Family study.
Not available
S-EPMC4069265 | biostudies-literature
UnknownLoss of SUMO-specific protease 2 causes isolated glucocorticoid deficiency by blocking adrenal cortex zonal transdifferentiation in mice.
Not available
S-EPMC9772323 | biostudies-literature
UnknownInteraction of haptoglobin with hemoglobin octamers based on the mutation αAsn78Cys or βGly83Cys.
Not available
S-EPMC3706102 | biostudies-literature
UnknownShort leukocyte telomere length predicts incidence and progression of carotid atherosclerosis in American Indians: the Strong Heart Family Study.
Not available
S-EPMC4069268 | biostudies-literature
UnknownBrentuximab vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2): a global, double-blind, randomised, phase 3 trial.
Not available
S-EPMC6436818 | biostudies-literature
UnknownOrganoids as a personalized medicine tool for ultra-rare mutations in cystic fibrosis: The case of S955P and 1717-2A>G.
Not available
S-EPMC7484254 | biostudies-literature
TranscriptomicsMaize Inbreds Exhibit High Levels of Copy Number Variation (CNV) and Presence/Absence Variation (PAV) in Genome Content
Following the domestication of maize over the past ,10,000 years, breeders have exploited the extensive genetic diversity of this species to mold its phenotype to meet human needs. The extent of structural variation, including copy number variation (CNV) and presence/absence variation (PAV), which a...
ORGANISM(S): Zea mays 
2009-11-19 | E-GEOD-16938 | biostudies-arrayexpress
ProteomicsMixed Alkyl/Aryl Phosphonates Identify Metabolic Serine Hydrolases as Antimalarial Targets
Malaria, caused by Plasmodium falciparum, remains a significant health burden. The barrier for developing anti-malarial drugs is the ability of the parasite to rapidly generate resistance. We previously demonstrated that Salinipostin A (SalA), a natural product, potently kills parasites by inhibitin...
ORGANISM(S): Homo sapiens (Human) Plasmodium falciparum (isolate 3D7) 
2024-07-15 | PXD051499 | Pride
Plasmodium Lipid metabolism Serine hydrolases Activity-based probes 
TranscriptomicsRegulation of Gene Expression and Parent-of-Origin Effects in Maize Hybrids
Heterosis (hybrid vigor) refers to the superior performance of hybrid progeny relative to their parents. Although widely exploited in agriculture, the mechanisms responsible for heterosis are not well understood. As a monoecious organism, a given maize plant can be used as both male and female par...
ORGANISM(S): Zea mays 
2009-11-20 | E-GEOD-16136 | biostudies-arrayexpress
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