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TranscriptomicsThe evolution of low mutation rates in experimental mutator populations of Saccharomyces cerevisiae
microarray experiment to test the gene expression in long term lines of mutator and non-mutator yeast. Here we use an experimental evolution approach to investigate the conditions required for evolution of a reduction in mutation rate and the mechanisms by which populations tolerate the accumulation...
ORGANISM(S): Saccharomyces cerevisiae 
2012-02-02 | E-GEOD-35440 | biostudies-arrayexpress
GenomicsChanges in intestinal permeability and gut microbiota following diet-induced weight loss in patients with metabolic dysfunction-associated steatohepatitis and liver fibrosis
We explore whether a low-energy diet intervention for Metabolic dysfunction-associated steatohepatitis (MASH) improves liver disease by means of modulating the gut microbiome. 16 individuals were given a low-energy diet (880 kcal, consisting of bars, soups, and shakes) for 12 weeks, followed by a st...
ORGANISM(S): mixed sample 
2024-12-31 | E-MTAB-14061 | biostudies-arrayexpress
TranscriptomicsNitrate Stress in Desulfovibrio vulgaris Hildenborough
Using data from microarray experiments, we investigated the effects of excess sodium nitrate on Desulfovibrio vulgaris. Keywords: stress response, time course Comparison of cells treated with 105 mM sodium nitrate to untreated cells at times of 0, 30, 60, 120, and 240 min.
ORGANISM(S): Desulfovibrio vulgaris str. Hildenborough 
2010-06-22 | E-GEOD-20079 | biostudies-arrayexpress
TranscriptomicsA new genome wide expression array and its application to eQTL mapping, synergy to other platforms
The study of gene expression as an intermediate phenotype in associating genotype to disease is growing rapidly. The success of this approach depends heavily on the availability of accurate, high throughput platforms for assaying expression levels of genome-wide gene sets. We evaluated a new platfor...
ORGANISM(S): Homo sapiens 
2012-04-29 | E-GEOD-15905 | biostudies-arrayexpress
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