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ProteomicsPP2A inhibition is a druggable MEK inhibitor resistance mechanism in KRAS-mutant lung cancer cells
TiO2-enriched and non-enriched samples and a pooled TiO2-enriched alkaline phosphatase treated sample from subconfluent A549 lung adenocarcinoma cells line. Cells were subjected to on of the 6 different treatments: Control sample, RNAi mediated depletion of PPP2R1A, CIP2A, or PME-1, and treatment w...
ORGANISM(S): Homo sapiens (Human) 
2018-10-11 | PXD009900 | Pride
Phosphoproteomics Pp2a A549 Lung cancer 
ProteomicsHeLa phosphoproteome regulated by PP2A related proteins
HeLa cells were treated with siRNAs of PP2A related proteins or with okadaic acid, in triplicates. Tryptic digests of extracted proteins were analyzed using a Q Exactive mass spectrometer, before and after TiO2 phosphopeptide enrichment. Data were searched with Mascot via Proteome Discoverer. For ph...
ORGANISM(S): Homo Sapiens (human) 
2020-02-19 | PXD016102 | JPOST Repository
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