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ProteomicsThe critical role of MLKL in hemorrhagic stroke and the therapeutic potential of its associated protein network
MLKL, as the executor of necroptosis and a critical factor in the inflammation, has been shown to be associated with the progression of hemorrhagic stroke. Studies identified MLKL is a promoting factor in this process, suggesting its potential as a therapeutic target to mitigate post-hemorrhagic str...
ORGANISM(S): Mus Musculus 
PXD056595 |
ProteomicsA proteomics landscape of circadian clock in mouse liver
As a circadian organ, liver executes diverse functions in different phase of the circadian clock. This process is believed to be driven by a transcription program. Here, we present a TF DNA-binding activity centered multi-dimensional proteomics landscape, including DNA-binding activity of TFs, the p...
ORGANISM(S): Mus Musculus 
PXD008771 |
ProteomicsSupplement data of project: A proteomics landscape of circadian clock in mouse liver
As a circadian organ, liver executes diverse functions in different phase of the circadian clock. This process is believed to be driven by a transcription program. Here, we present a TF DNA-binding activity centered multi-dimensional proteomics landscape, including DNA-binding activity of TFs, the p...
ORGANISM(S): Mus Musculus 
PXD008862 |
ProteomicsA proteomic landscape of macrophage in mouse tissues
Macrophages, locating in essentially all tissues, are critical for innate immune responses and involved in the tissue homeostasis. Distinct macrophages populations in different tissues exhibited diverse gene expressions and biological processes. Previous studies have accessed the molecular signature...
ORGANISM(S): Mus Musculus 
PXD021583 |
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