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ProteomicsThe cleavage site identification of Gm11437 by LC-MSMS
This study first identified the gut-derived factor Famsin, which is the N-terminal cleavage product of the single-transmembrane protein Gm11437, revealed a new liver-gut signaling axes involved in the regulation of energy homeostasis
ORGANISM(S): Mus musculus (Mouse) 
2023-03-21 | PXD024577 | Pride
To determine the amino acid sequence of gm11437 n-terminal product purified from sf9 conditional medium 
TranscriptomicsGene expression profiling in BCR/ABL expressing LSCs and BCR/ABL expressing Alox5-/-LSCs
We previously demonstrated that Alox5 deficiency impairs the function of LSCs and prevents the initiation of BCR-ABL-induced CML. To identify the pathways in which Alox5 gene regulates function of LSCs, we performed a comparative DNA microarray analysis using total RNA isolated from non-BCR-ABL-expr...
ORGANISM(S): Mus musculus 
2011-05-17 | E-GEOD-29347 | biostudies-arrayexpress
TranscriptomicsGene expression profiling in WT and Alox15-/- HSCs
To understand the underlying mechanism by which Alox15 gene is required by HSCs, we performed a comparative DNA microarray analysis using total RNA isolated from wild type Lin-Sca-1+c-Kit+, Alox5-/- Lin-Sca-1+c-Kit+. The result was validated by quantitative real-time PCR analysis of wild type Lin-Sc...
ORGANISM(S): Mus musculus 
2011-05-17 | E-GEOD-29348 | biostudies-arrayexpress
UnknownFamsin, a novel gut-secreted hormone, contributes to metabolic adaptations to fasting via binding to its receptor OLFR796.
Not available
S-EPMC10066382 | biostudies-literature
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