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ProteomicsTargeting MGAT4A-mediated N-glycosylation as a therapeutic strategy to inhibit glioblastoma stem cell invasion
Proteomic glycosylation mapping via mass spectrometry and co-immunoprecipitation assays elucidates the MGAT4A interaction with EGFR, catalyzing N-glycosylation at the EGFR N604 site.
ORGANISM(S): Homo sapiens (Human) 
2025-01-18 | PXD052176 | Pride
Human Cell N-glycoproteomics Label-free 
ProteomicsMAGL Targeted PROTAC Degrader Simultaneously Enhances P53 for Synergistic Treatment of Glioblastoma Stem Cell
This study focuses on the protein degradation effects of the MAGL inhibitor JZL184 and the newly synthesized MAGL-PROTAC on MAGL.
ORGANISM(S): Homo Sapiens 
2024-12-02 | PXD058506 |
TranscriptomicsEvx1as and EVX1 knockouts by CRISPR
We report that long noncoding RNAs contribute to transcription and developmental process. Thousands of lncRNAs have been identified in the whole genome, and tend to located closely to protein-coding genes. To study position relationship between lncRNA and protein-coding genes, we classified all of l...
ORGANISM(S): Mus musculus 
2016-03-24 | E-GEOD-70419 | biostudies-arrayexpress
ProteomicsPotential binding partners of NUDT13 in DLD-1
To explore the role of NUDT13 in the initiation and progression of CRC, we performed NUDT13 immunoprecipitation in DLD-1 following LC-MS/MS analysis.
ORGANISM(S): Homo Sapiens 
PXD041430 |
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