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ProteomicsIP-MS of human YKT6 upon mutation of possible ULK1-phosphorylation sites
Autophagy is a catabolic process during which cytosolic material is enwrapped in a newly formed double membrane structure called the autophagosome, and subsequently targeted for degradation in the lytic compartment of the cell. The fusion of autophagosomes with the lytic compartment is a tightly reg...
ORGANISM(S): Homo sapiens (Human) 
2023-03-02 | PXD038148 | Pride
Human Q exactive hf Hela Ip-ms Ykt6 Lfq 
GenomicsYKT6 promotes bladder cancer progression by stabilizing β-Catenin via USP7-mediated deubiquitination
YKT6 promotes bladder cancer progression by stabilizing β-Catenin via USP7-mediated deubiquitination
PRJNA1244377 | ENA
TranscriptomicsYKT6 promotes bladder cancer progression by stabilizing β-Catenin via USP7-mediated deubiquitination
Bladder cancer (BLCA) remains a highly lethal genitourinary malignancy with complex tumor biology and limited therapeutic strategies. This study investigates the oncogenic role of YKT6, a SNARE protein, in BLCA progression and molecular mechanisms. We demonstrate that YKT6 is significantly upregulat...
ORGANISM(S): Homo sapiens 
2025-11-27 | GSE293406 | GEO
ProteomicsYKT6 is essential for male fertility by promoting meiosis progression through vesicular transport regulation during spermatogenesis of mice
The tetraploid spermatocytes of postnatal days (PD) 16 Ykt6-Ctrl and Ykt6-cKO mice obtained by fluorescence-activated cell sorting were subjected to proteomics analysis. After three rinses with phosphate-buffered saline (PBS), the samples were gathered into tubes containing lysis buffer, flash froze...
ORGANISM(S): Mus Musculus 
PXD063213 |
UnknownPhosphorylation of Ykt6 SNARE Domain Regulates Its Membrane Recruitment and Activity.
Not available
S-EPMC7696345 | biostudies-literature
UnknownNon-canonical role of the SNARE protein Ykt6 in autophagosome-lysosome fusion.
Not available
S-EPMC5937789 | biostudies-literature
UnknownLipid Regulated Intramolecular Conformational Dynamics of SNARE-Protein Ykt6.
Not available
S-EPMC4974504 | biostudies-literature
UnknownDifferent conformational dynamics of SNARE protein Ykt6 among yeast and mammals.
Not available
S-EPMC10388204 | biostudies-literature
UnknownDouble prenylation of budding yeast Ykt6 regulates cell wall integrity and autophagy.
Not available
S-EPMC12001115 | biostudies-literature
UnknownComprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinoma.
Not available
S-EPMC11460176 | biostudies-literature
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