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TranscriptomicsExpression data from Satb1- and control-transduced LSK Flt3- cells
How hematopoietic stem cells (HSCs) produce specific lineages is not well understood. We searched for key factors that direct HSC to lymphopoiesis. Comparing gene expression profiles for HSCs and early lymphoid progenitors revealed that Satb1, a global chromatin regulator, was significantly induced ...
ORGANISM(S): Mus musculus 
2013-04-01 | E-GEOD-45566 | biostudies-arrayexpress
TranscriptomicsGenes affected by SFRP5 overexpression in LSK cells and CLP
To understand gene expression signatures between wild-type and SFRP5-overexpressing cells To examine genes regulated by SFRP5 expression, sets of microarrays were conducted with Lin- c-kitHi Sca-1+ cells and Lin- c-kitLo Sca-1Lo IL7Rα+ CLP-enriched cells derived from adult bone marrow of SFRP5-tra...
ORGANISM(S): Mus musculus 
2014-03-20 | E-GEOD-55646 | biostudies-arrayexpress
TranscriptomicsGenes affected by Satb1 deficiency in HSC, LMPP and CLP
To understand gene expression signatures between wild-type and Satb1-deficient cells To examine genes regulated by Satb1 expression, sets of microarrays were conducted with Lin- c-kitHi Sca-1+ Flt3- HSC-enriched cells, Lin- c-kitHi Sca-1+ Flt3+LMPP-enriched cells, and Lin- c-kitLo Sca-1Lo IL7Rα+ C...
ORGANISM(S): Mus musculus 
2013-03-20 | E-GEOD-45299 | biostudies-arrayexpress
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