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TranscriptomicsCurcumin Extends Lifespan, Improves Healthspan, and Modulates the Expression of Age-Associated Aging Genes in Drosophila melanogaster
Curcumin, a yellow pigment extracted from the rhizome of the plant Curcuma longa (turmeric) has been widely used as a spice and herbal medicine in Asia. It has been suggested to have many biological activities such as anti-oxidative, anti-inflammatory, anti-cancer, chemopreventive, and anti-neurodeg...
ORGANISM(S): Drosophila melanogaster 
2010-04-06 | E-GEOD-21182 | biostudies-arrayexpress
TranscriptomicsTranscriptome and translatome landscape of Streptomyces coelicolor M145
We have integrated nucleotide resolution genome-scale measurements of the transcriptome and translatome of the Streptomyces coelicolor A3(2), the model antibiotic-producing actinomycete. Our systematic study determined 3,473 transcription start sites, leading to discovery of a high proportion (~21%)...
ORGANISM(S): Streptomyces coelicolor 
2016-05-28 | E-GEOD-69350 | biostudies-arrayexpress
TranscriptomicsSTAT3-mediated CD133 upregulation promotes hepatocellular carcinoma
We identified a novel mechanism by which IL-6/STAT3 signaling up-regulates CD133 expression and promotes HCC progression. STAT3 activation upregulates the expression of CD133 during liver carcinogenesis. Targeting STAT3-mediated CD133 overexpression may represent a promising therapeutic strategy for...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-60194 | biostudies-arrayexpress
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