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GenomicsHEB and E2A function as SMAD/FOXH1 cofactors
Nodal signaling, mediated through SMAD transcription factors, is necessary for pluripotency maintenance and endoderm commitment. We have identified a new motif, termed SMAD Complex Associated (SCA) that is bound by SMAD2/3/4 and FOXH1 in human embryonic stem cells (hESCs) and derived endoderm. We de...
ORGANISM(S): Xenopus (Silurana) tropicalis 
2011-08-23 | E-GEOD-30146 | biostudies-arrayexpress
GenomicsChromatin and Transcriptional Signatures for Nodal Signaling During Endoderm Formation in hESCs
To elucidate the Nodal transcriptional network that governs endoderm formation, we used ChIP-Seq to identify genomic targets for SMAD2/3, SMAD3, SMAD4, FOXH1 and the active and repressive chromatin marks, H3K4me3 and H3K27me3, in human embryonic stem cells (hESCs) and derived endoderm. We demonstrat...
ORGANISM(S): Homo sapiens 
2011-05-21 | E-GEOD-29422 | biostudies-arrayexpress
UnknownFate of Surgical Patients with Small Nonfunctioning Pancreatic Neuroendocrine Tumors: An International Study Using Multi-Institutional Registries.
Not available
S-EPMC8870171 | biostudies-literature
Genomicsena-DATASET-asan-ccgd-27-09-2019-00:22:21:191-59 - samples
231 HCC exome sequencing with Sureselect 50Mb
EGAD00001005361 | EGA
GenomicsThese are from Korean HCC samples with exome sequencing
Hepatic resection is the most curative treatment option for early-stage hepatocellular carcinoma, but is associated with a high recurrence rate, which exceeds 50% at 5 years after surgery. Understanding the genetic basis of hepatocellular carcinoma at surgically curable stages may enable the identif...
EGAS00001000604 | EGA
Genomicswhole exome sequencing of Korean hepatocellular carcinomas
Data Access Committee EGAC00001000329
EGAC00001000329 | EGA
UnknownLaparoscopic vs Open Distal Gastrectomy for Locally Advanced Gastric Cancer: 5-Year Outcomes of the KLASS-02 Randomized Clinical Trial.
Not available
S-EPMC9301593 | biostudies-literature
UnknownGenome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population.
Not available
S-EPMC10220065 | biostudies-literature
UnknownIntegrating sequence and array data to create an improved 1000 Genomes Project haplotype reference panel.
Not available
S-EPMC4338501 | biostudies-literature
UnknownIntegrative annotation of variants from 1092 humans: application to cancer genomics.
Not available
S-EPMC3947637 | biostudies-literature
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