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Arabidopsis lesion initiation 3 mutant
ORGANISM(S): Arabidopsis thaliana 
Background: Progressive neurological dysfunction is a key aspect of human aging. Because of underlying differences in the aging of mice and humans, useful mouse models have been difficult to obtain and study. We have used gene-expression analysis and polymorphism screening to study molecular senesce...
ORGANISM(S): Mus musculus 
Transcriptional profiling of NK cell lines (NKL & NKYS) with DMSO or vorinostat
ORGANISM(S): Homo sapiens 
The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account for 97% of the photoreceptors; however, in the absence of Nrl (Nrl-/-), no rods are present and a co...
ORGANISM(S): Mus musculus 
TDP-43 is the major disease-associated protein involved in the pathogenesis and progression of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions linked to TDP-43 pathology (FTLD-TDP). Abnormal phosphorylation, truncation and cytoplasmic mis...
ORGANISM(S): Homo Sapiens (human) 
We have analyzed and compared the post-translational modifications in the pathological tau proteins prepared from a wide range of tauopathies.
ORGANISM(S): Homo Sapiens (human) 
LC-MS/MS analysis of post-translational modifications in alpha-synuclein of five MSA cases.
ORGANISM(S): Homo Sapiens (human) 
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