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TranscriptomicsTranscription profiling of hippocampus and retina from two rare inbred mouse models of accelerated neurological senescence ( SAMP8 and SAMP10) and a related wild type strain SAMR1 to study molecular senescence of the retina and hippocampus.
Background: Progressive neurological dysfunction is a key aspect of human aging. Because of underlying differences in the aging of mice and humans, useful mouse models have been difficult to obtain and study. We have used gene-expression analysis and polymorphism screening to study molecular senesce...
ORGANISM(S): Mus musculus 
2007-11-14 | E-GEOD-6238 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Arabidopsis len3 mutants
Arabidopsis lesion initiation 3 mutant
ORGANISM(S): Arabidopsis thaliana 
2008-04-17 | E-MEXP-1084 | biostudies-arrayexpress
TranscriptomicsComprehensive gene expression profiles of NK cell neoplasms identify vorinostat as an effective drug candidate
Transcriptional profiling of NK cell lines (NKL & NKYS) with DMSO or vorinostat
ORGANISM(S): Homo sapiens 
2013-01-24 | E-MTAB-1410 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse developing and mature Nrl -/- retina against wild type controls
The rod photoreceptor-specific neural retina leucine zipper protein Nrl is essential for rod differentiation and plays a critical role in regulating gene expression. In the mouse retina, rods account for 97% of the photoreceptors; however, in the absence of Nrl (Nrl-/-), no rods are present and a co...
ORGANISM(S): Mus musculus 
2009-10-30 | E-GEOD-8972 | biostudies-arrayexpress
ProteomicsMass spectrometric analysis of accumulated TDP-43 in amyotrophic lateral sclerosis brains
TDP-43 is the major disease-associated protein involved in the pathogenesis and progression of amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration with ubiquitin-positive inclusions linked to TDP-43 pathology (FTLD-TDP). Abnormal phosphorylation, truncation and cytoplasmic mis...
ORGANISM(S): Homo Sapiens (human) 
2020-03-01 | PXD012920 | JPOST Repository
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