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TranscriptomicsTranscription profiling of mouse testis from Tslc1-/- knockouts
TSLC1/IGSF4, an immunoglobulin superfamily molecule, is predominantly expressed in the brain, lung, and testis and plays important roles in epithelial cell adhesion, cancer invasion, and synapse formation. We generated Tslc1/Igsf4-deficient mice by disrupting exon 1 of the gene and found that Tslc1...
ORGANISM(S): Mus musculus 
2008-06-12 | E-GEOD-3676 | biostudies-arrayexpress
TranscriptomicsEnhanced engraftment, proliferation, and therapeutic potential in heart using optimized iPSC-derived cardiomyocytes
Human pluripotent stem cell-derived cardiomyocytes (CMs) are a promising tool for cardiac cell therapy. To optimize graft cells for cardiac reconstruction, we compared the engraftment efficiency of intramyocardially-injected undifferentiated-induced pluripotent stem cells (iPSCs), day4 mesodermal ce...
ORGANISM(S): Homo sapiens 
2016-07-03 | E-GEOD-60634 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells [iPSC_ESC_lines]
The variation among induced pluripotent stem cells (iPSCs) in their differentiation capacity to specific lineages is frequently attributed to somatic memory. In this study, we compared hematopoietic differentiation capacity of 35 human iPSC lines derived from four different tissues and four embryoni...
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-75096 | biostudies-arrayexpress
TranscriptomicsReprogramming-associated aberrant DNA methylation determines hematopoietic differentiation capacity of human induced pluripotent stem cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2016-06-29 | E-GEOD-60924 | biostudies-arrayexpress
TranscriptomicsSynthetic mRNA switches for detection and purification of cardiomyocytes and endothelial cells derived from human pluripotent stem cells [miRNA]
We designed microRNA-responsive, modified mRNA switches (miR-switches) that quantitatively control their own translation level by determining the miRNA activities. We found that the three miR-switches (i.e., miR-1-, miR-208-, and miR-499-switches) enable to purify cardiomyocytes differentiated from ...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-60631 | biostudies-arrayexpress
TranscriptomicsSynthetic mRNA switches for detection and purification of cardiomyocytes and endothelial cells derived from human pluripotent stem cells [mRNA]
We designed microRNA-responsive, modified mRNA switches (miR-switches) that quantitatively control their own translation level by determining the miRNA activities. We found that the three miR-switches (i.e., miR-1-, miR-208-, and miR-499-switches) enable to purify cardiomyocytes differentiated from ...
ORGANISM(S): Homo sapiens 
2015-05-20 | E-GEOD-60632 | biostudies-arrayexpress
TranscriptomicsDevelopment of a high-density oligo microarray of cassava, an important tropical crop
We developed a 60-mer oligonucleotide Agilent microarray representing about 20,000 cassava genes and applied it to expression profiling under drought stress. We demonstrated that our microarray is an useful tool for analyzing the cassava transcriptome and that it can be applied to various cassava sp...
ORGANISM(S): Manihot esculenta subsp. peruviana 
2012-06-14 | E-GEOD-31749 | biostudies-arrayexpress
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