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TranscriptomicsGenome-wide gene expression profiling analysis of bone metastases of human non-small cell lung cancer (NSCLC) in mice
Using a multiorgan metastasis model of human NSCLC cells (ACC-LC319/bone2) in NK cell-depleted SCID mice, we attempted to identify genes involved in the organ-selective nature of lung cancer-metastasis process, especially bone metastasis. Genome-wide gene expression profile of 15 metastatic lesions ...
ORGANISM(S): Homo sapiens 
2012-02-21 | E-GEOD-29391 | biostudies-arrayexpress
TranscriptomicsGene expression profiles of 5 cancer cell lines
Gene expression profiles of 5 cancer cell lines, including lung cancer (SBC-5 (duplicate samples), ACC-LC319/bone2, NCI-H1048); and breast cancer (ZR75.1, HCC1397) were analyzed. Cells were cultured following the guidelines published somewhere, and at confluent ~ 80% cells were extracted RNA for mic...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-40559 | biostudies-arrayexpress
TranscriptomicsInvolvement of transcription factor early growth response 4 (EGR4) in lung cancer bone metastasis
EGR4 (early growth response 4), a transcription factor, was previously shown to be up-regulated in lung cancer bone metastasis, compared with its expression in metastasis in other organs, using a multiorgan metastasis model of human small-cell lung cancer cells (SBC-5) in NK cell-depleted SCID mice ...
ORGANISM(S): Homo sapiens 
2013-04-01 | E-GEOD-40558 | biostudies-arrayexpress
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