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MetabolomicsFaecal microbiota transplant from aged donor mice affects spatial learning and memory via modulating hippocampal synaptic plasticity- and neurotransmission-related proteins in young recipients

BACKGROUND: The gut-brain axis and the intestinal microbiota are emerging as key players in health and disease. Shifts in intestinal microbiota composition affect a variety of systems, however, evidence of their direct impact on cognitive functions is still lacking. We tested whe...

2021-12-17 | MTBLS1437 | MetaboLights
TranscriptomicsTranscription profiling of mouse ck-OBF-1 transgene
The Lck-OBF-1 construct used to generate transgenic mice contains an N-terminally HA epitope-tagged human OBF-1 cDNA under the control of the murine proximal lck promoter (-3100 to +23 relative to the transcription start site) that was purified by electroelution. Transgenic mouse lines were obtained...
ORGANISM(S): Mus musculus 
2006-10-25 | E-MEXP-85 | biostudies-arrayexpress
TranscriptomicsYoung Adult reference tiling array
modENCODE_submission_656 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23280 | biostudies-arrayexpress
TranscriptomicsYoung Adult Cephalic sheath (CEPsh) tiling array
modENCODE_submission_660 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commerically available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23284 | biostudies-arrayexpress
GenomicsDiscovery and Characterization of Super-Enhancer Associated Dependencies in Diffuse Large B-Cell Lymphoma
Diffuse Large B-Cell Lymphoma (DLBCL) is a biologically heterogeneous and clinically aggressive disease. Here, we explore the role of BET bromodomain proteins in DLBCL, using integrative chemical genetics and functional epigenomics. We observe highly asymmetric loading of BRD4 at enhancers, with app...
ORGANISM(S): Homo sapiens 
2013-12-10 | E-GEOD-46663 | biostudies-arrayexpress
Transcriptomicspathogen_Pluminscens_25dC_24hr_exposure_post-adulthood_N2_tiling_array
modENCODE_submission_486 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commercially available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23272 | biostudies-arrayexpress
Transcriptomicspathogen_Smarcescens_25dC_48hr_exposure_post-adulthood_N2_tiling_array
modENCODE_submission_488 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commercially available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23274 | biostudies-arrayexpress
Transcriptomicspathogen_Smarcescens_25dC_24hr_exposure_post-adulthood_N2_tiling_array
modENCODE_submission_489 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commercially available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23275 | biostudies-arrayexpress
Transcriptomicspathogen_controlOP50_25dC_48hr_exposure_post-adulthood_N2_tiling_array
modENCODE_submission_490 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commercially available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23276 | biostudies-arrayexpress
Transcriptomicspathogen_controlOP50_25dC_24hr_exposure_post-adulthood_N2_tiling_array
modENCODE_submission_491 This submission comes from a modENCODE project of Robert Waterston. For full list of modENCODE projects, see http://www.genome.gov/26524648 Project Goal: Our experiments are designed to detect all C. elegans transcripts by hybridizing RNA to commercially available genome til...
ORGANISM(S): Caenorhabditis elegans 
2010-08-04 | E-GEOD-23277 | biostudies-arrayexpress
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