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TranscriptomicsConditional loss of ErbB3 delays mammary gland hyperplasias induced by mutant PIK3CA but does not affect mammary tumor latency, gene expression or signaling
Mutations in PIK3CA, the gene encoding the p110α subunit of PI3K, induce transformation of mammary epithelial cells (MEC). Studies suggest the transforming action of mutant PIK3CA requires binding to activated receptor tyrosine kinases or adaptors. We examined in transgenic mice if ErbB3, a powerful...
ORGANISM(S): Mus musculus 
2013-06-20 | E-GEOD-43037 | biostudies-arrayexpress
TranscriptomicsAn Atlas of Bovine Gene Expression Reveals Novel Distinctive Tissue Characteristics and Evidence for Improving Genome Annotation
Background: A comprehensive transcriptome survey, or "gene atlas", provides information essential for a complete understanding of the genomic biology of an organism. We present an atlas of RNA abundance for 92 adult, juvenile and fetal cattle tissues and 3 cattle cell lines. Results: The ...
ORGANISM(S): Bos taurus 
2010-09-28 | E-GEOD-21544 | biostudies-arrayexpress
UnknownLarge-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Not available
S-EPMC9700438 | biostudies-literature
UnknownDisparities in HIV Viral Load Suppression by Race/Ethnicity Among Men Who Have Sex with Men in the HIV Outpatient Study.
Not available
S-EPMC7528768 | biostudies-literature
MetabolomicsIntegrated omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: the crucial role of lipid metabolism
Pandemic influenza viruses modulate pro-inflammatory responses that can lead to immunopathogenesis. We present an extensive and systematic profiling of lipids, metabolites and proteins in respiratory compartments of ferrets infected with either 1918 or 2009 human pandemic H1N1 influenza viruses. Int...
2016-05-11 | MTBLS196 | MetaboLights
UnknownDecreased Self-reported Physical Fitness Following SARS-CoV-2 Infection and the Impact of Vaccine Boosters in a Cohort Study.
Not available
S-EPMC10733205 | biostudies-literature
UnknownEarly trajectories of virological and immunological biomarkers and clinical outcomes in patients admitted to hospital for COVID-19: an international, prospective cohort study.
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S-EPMC11181148 | biostudies-literature
UnknownThe <i>FANCM</i>:p.Arg658* truncating variant is associated with risk of triple-negative breast cancer.
Not available
S-EPMC6825205 | biostudies-literature
UnknownGenetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function.
Not available
S-EPMC4735748 | biostudies-literature
UnknownGenome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer.
Not available
S-EPMC4549775 | biostudies-literature
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