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Pichia pastoris (Komagataella phaffi) transcription factor Mxr1p is known to regulate multiple metabolic pathways by binding to Mxr1p response elements of target genes. Mxr1p possesses a transactivation domain within the N-terminal 400 amino acids (Mxr1N400) which is functional during methanol metab...
ORGANISM(S): Komagataella pastoris 
2021-09-22 | GSE146829 | GEO
Previous results suggest that Bmh might inhibit the activity of the transcription factor Adr1 after binding to Adr1-dependent promoters. In a strain lacking the two major histone deacetylases, Hda1 and Rpd3 (hdac?), Adr1 is bound to its target promoters recruiting what appears to be an inactive RNA ...
ORGANISM(S): Saccharomyces cerevisiae 
To identify novel targets of Mxr1p in Pichia pastoris cultured in methanol
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