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TranscriptomicsExpression data from young and adult mice after over expression of self MHC class l protein in skeletal muscle.
Over expression of MHC Class l protein in skeletal muscle causes myositis. Phenotype after expression in young mice is more severe. We performed gene expression profiling on young and adult mice after over expression of self MHC class l protein in skeletal muscle Muscle from young ( early) , adult ...
ORGANISM(S): Mus musculus 
2009-06-02 | E-GEOD-14997 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling from young, old, healthy, or injured rat iliac arteries.
Transcriptional profiling from young, old, healthy, or injured rat iliac arteries. We studied the gene expression profile in a model of mechanical vascular injury in the iliac artery of aging (22 months old) and young rats (4 months old). We investigated aging-related variations in gene expression a...
ORGANISM(S): Rattus norvegicus 
2011-10-18 | E-GEOD-29255 | biostudies-arrayexpress
TranscriptomicsSmall RNA-Seq Reveals similar miRNA Transcriptome in Children and Young Adults with T-ALL and Indicates miR-143-3p as Novel Candidate Tumor Suppressor in This Leukemia
We aimed to identify miRNAs and pathways specifically deregulated in adolescent and young adult (AYA) T-ALL patients. Small RNA-seq showed no major differences between AYA and pediatric T-ALL, but it revealed downregulation of miR-143-3p in T-ALL patients. Prediction algorithms identified several kn...
ORGANISM(S): Homo sapiens 
2022-09-06 | E-MTAB-11987 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli during lag phase of cells previously starved in stationary phase for 1 day (young cells) or 16 days (old cells)
transcriptional response during lag phase (several time points) of bacterial cells starved previously in stationary phase for 1 day (young cells) and 16 days (old cells)
ORGANISM(S): Escherichia coli 
2009-10-22 | E-MEXP-2379 | biostudies-arrayexpress
TranscriptomicsmRNA microarray analysis on young adult Caenorhabditis elegans, Drosophila melanogaster, and Danio rerio exposed to benzene, toluene, and formaldehyde
This SuperSeries is composed of the following subset Series: GSE23013: mRNA microarray analysis on young adult Caenorhabditis elegans exposed to benzene, toluene, formaldehyde and a BTF mix GSE24845: mRNA microarray analysis on young adult Drosophila exposed to benzene, toluene, and formaldehyde GSE...
ORGANISM(S): Danio rerio 
2011-12-31 | E-GEOD-24923 | biostudies-arrayexpress
TranscriptomicsA Parallel Study of mRNA and MicroRNA Profiling of Peripheral Blood in Young Adult Women
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-08-13 | E-GEOD-30205 | biostudies-arrayexpress
TranscriptomicsmRNA microarray analysis on young adult Caenorhabditis elegans exposed to MWCNT
In order to evaluate the identification of genes and pathways, the global gene expression profiles were assessed in response to multiwall carbon nanotube (MWCNT) on the soil nematode, Caenorhabditis elegans. We performed whole genome DNA microarray experiments with subsequent quantitative analysis c...
ORGANISM(S): Caenorhabditis elegans 
2011-12-31 | E-GEOD-24847 | biostudies-arrayexpress
TranscriptomicsCircadian mRNA expression in skeletal muscle of young and aged mice
Aging animals undergo a variety of changes in molecular processes. Among these, the cellular circadian clock has been shown to change as animals age. Moreover, there is evidence that also core circadian clock proteins could influence the ageing behavior of vertebrates. To investigate the interplay ...
ORGANISM(S): Mus musculus 
2016-03-31 | E-GEOD-75523 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans treated with UV-C radiation
We used gene expression profiling to address several specific questions that arose in a study of repair of ultraviolet C radiation in C elegans, as well as to generate hypotheses regarding the possible mechanism(s) of decreased DNA repair observed in old adults in that study. This analysis was perfo...
ORGANISM(S): Caenorhabditis elegans 
2008-06-13 | E-GEOD-4766 | biostudies-arrayexpress
TranscriptomicsChIP-chip of E. coli K-12 MG1655 with antibody against PurR-8myc under various conditions.
We integrated transcription factor binding regions and mRNA transcript abundance to elucidate the PurR regulon experimentally. To measure transcription factor binding at a genome scale, we employed a ChIP-chip method to derivative strains of E. coli K-12 MG1655 harboring PurR-8myc under various con...
ORGANISM(S): Escherichia coli str. K-12 substr. MG1655 
2011-06-14 | E-GEOD-26589 | biostudies-arrayexpress
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