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MetabolomicsPostprandial Metabolism is Impaired in Overweight Normoglycemic Young Adults without Family History of Diabetes

While the risk factors for Type 2 diabetes (T2DM) are known, early predictive markers of transition from normal to a prediabetes state are unidentified. We studied the basal metabolism and metabolic response to a mixed-meal challenge in 110 healthy subjects in the age group of 18 to 40 years (Mal...

2019-03-14 | MTBLS743 | MetaboLights
TranscriptomicsDifferences in genome-wide gene expression response in PBMCs between young and old men upon caloric restriction
Caloric restriction (CR) is considered to increase lifespan and to prevent various age-related diseases in different non-human organisms. Only a limited number of CR studies have been performed in humans, and results put CR as a beneficial tool to decrease risk factors in several age-related disease...
ORGANISM(S): Homo sapiens 
2016-10-24 | E-GEOD-63117 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of E. coli during lag phase of cells previously starved in stationary phase for 1 day (young cells) or 16 days (old cells)
transcriptional response during lag phase (several time points) of bacterial cells starved previously in stationary phase for 1 day (young cells) and 16 days (old cells)
ORGANISM(S): Escherichia coli 
2009-10-22 | E-MEXP-2379 | biostudies-arrayexpress
TranscriptomicsEffect of acute creatine monohydrate supplementation on skeletal muscle transcriptome
Expression profiling of vastus lateralis muscle of young, healthy, non-obese men supplemented with creatine monohydrate vs. placebo for 10 days. Results identify transcriptional pathways activated in skeletal muscles as a result of acute creatine monohydrate supplementation. Keywords: Supplementatio...
ORGANISM(S): Homo sapiens 
2010-06-11 | E-GEOD-7877 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of hearts from young (2-4 month) and moderately aged (16-18 month) C57/Bl6 male mice subjected to i) 20 min global ischaemia, 60 min reperfusion or ii) 80 min aerobic perfusion/normoxia
Hearts from young (2-4 month) and moderately aged (16-18 month) C57/Bl6 male mice were subjected to i) 20 min global ischaemia, 60 min reperfusion or ii) 80 min aerobic perfusion/normoxia.
ORGANISM(S): Mus musculus 
2005-12-31 | E-MEXP-496 | biostudies-arrayexpress
TranscriptomicsEpigenetic analysis of healthy young men following a control and high-fat overfeeding diet
Genome-wide DNA methylation profiling of healthy young men following a control and high-fat overfeeding diet using Illumina's Infinium 27k Human DNA methylation Beadchip v. 1.2. DNA methylation profiles were obtained for 27,578 CpG sites in human skeletal muscle. Randomized cross-over desgin, where ...
ORGANISM(S): Homo sapiens 
2012-09-12 | E-GEOD-36166 | biostudies-arrayexpress
MetabolomicsEFO: In preparation - Early Metabolic Predictors of Type 2 Diabetes Mellitus in Normoglycemic Adults: Insights from Six-Year Prospective Cohort Study

INTRODUCTION: Type 2 Diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance and hyperglycemia, often preceded by latent metabolic disruptions. Early detection of metabolic alterations can facilitate timely intervention to delay or prevent T2DM onset. Metaboli...

2025-08-04 | MTBLS10965 | MetaboLights
UnknownCigarette, E-Cigarette and Waterpipe Use among Young Adults: Differential Cognitions about These Three Forms of Smoking.
Not available
S-EPMC7312077 | biostudies-literature
TranscriptomicsDivergent genome expression profiles during hepatic ischemia in young and adult mice
Experimental Design: 1. The goal of the experiment: Age-Related Genome Expression Profiles During Hepatic Ischemia 2. Brief description of the experiment: Hepatic ischemia/reperfusion (I/R) injury is a complication of liver surgery, transplantation and shock and differs with age. In the present stu...
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10652 | biostudies-arrayexpress
TranscriptomicsHepatic response to ischemia and reperfusion: young and adult mice
This SuperSeries is composed of the following subset Series: GSE10652: Divergent genome expression profiles during hepatic ischemia in young and adult mice GSE10654: Age-dependent gene expression profiles after hepatic ischemia/reperfusion in mice Keywords: SuperSeries Refer to individual Series
ORGANISM(S): Mus musculus 
2010-05-26 | E-GEOD-10657 | biostudies-arrayexpress
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