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TranscriptomicsscATAC-seq of mouse liver tissue derived from young and old mice
We investigate if the differences in phenotype and transcriptome over age might be explained by an underlying change on the epigenetic level. We performed single-cell ATAC sequencing using the 10x Chromium platform. We profiled 4838 nuclei prepared from 3 young liver tissues and 3361 nuclei from 3 o...
ORGANISM(S): Mus musculus 
2023-02-20 | E-MTAB-12706 | biostudies-arrayexpress
TranscriptomicsscATAC-seq of mouse liver tissue derived from young and old mice II
We investigate if the differences in phenotype and transcriptome over age might be explained by an underlying change on the epigenetic level. We performed single-cell ATAC sequencing using the 10x Chromium platform. We profiled 2259 nuclei prepared from 3 young liver tissues and 2490 nuclei from 3 o...
ORGANISM(S): Mus musculus 
2023-11-09 | E-MTAB-12560 | biostudies-arrayexpress
UnknownHierarchical investigation of genetic influences on response inhibition in healthy young adults.
Not available
S-EPMC5737791 | biostudies-literature
UnknownConsidering Clinical Implementation of Polygenic Scores in Hereditary Cancer Risk Assessment: Recipients' Perspectives on Influencing Factors and Strategies.
Not available
S-EPMC12559137 | biostudies-literature
TranscriptomicsPromoter proximal pausing and its regulation by c-Myc in embryonic stem cells: ChIP-chip
Recruitment of the RNA Polymerase II (Pol II) transcription initiation apparatus to promoters by specific DNA binding transcription factors is well recognized as a key regulatory step in gene expression. We describe here evidence that promoter-proximal pausing is a general feature of transcription ...
ORGANISM(S): Mus musculus 
2010-04-02 | E-GEOD-20529 | biostudies-arrayexpress
TranscriptomicsBulk RNA-seq of organoids derived from young and old mice livers
We set up liver-derived organoids to study the ageing progenitor population. We detected epigenetic and transcriptional memory in organoids derived from old mice accompanied by alterations in drug and fatty acid metabolism pathways, similar to phenotypes observed in the liver itself.
ORGANISM(S): Mus musculus 
2024-11-30 | E-MTAB-11060 | biostudies-arrayexpress
UnknownExploring the facilitators and barriers to using an online infertility risk prediction tool (FoRECAsT) for young women with breast cancer: a qualitative study protocol.
Not available
S-EPMC7044829 | biostudies-literature
UnknownModerately hypofractionated versus conventionally fractionated radiation therapy with temozolomide for young and fit patients with glioblastoma: an institutional experience and meta-analysis of literature.
Not available
S-EPMC9648463 | biostudies-literature
UnknownFactors associated with COVID-19 vaccination in young children.
Not available
S-EPMC10868559 | biostudies-literature
UnknownCannabis Use Frequency and Cannabis-Related Consequences in High-Risk Young Adults Across Cannabis Legalization.
Not available
S-EPMC10534274 | biostudies-literature
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