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TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [Cervix samples series 1]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39013 | biostudies-arrayexpress
TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [Bladder samples]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39016 | biostudies-arrayexpress
TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [Cervix samples series 2]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39014 | biostudies-arrayexpress
TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [cell lines]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39066 | biostudies-arrayexpress
TranscriptomicsGlobal gene expression changes in patient-derived CML cell line K562 after short- and long-term BCR-ABL kinase inhibition.
K562 cells were treated with the BCR-ABL kinase inhibitor dasatinib over an extended period of time to determine how BCR-ABL inhibition affects BCR-ABL-dependent negative feedback and erythropoietin receptor (EPO-R) signaling. Specifically, what types of changes (upregulation versus downregulation)...
ORGANISM(S): Homo sapiens 
2013-09-24 | E-GEOD-51083 | biostudies-arrayexpress
TranscriptomicsStability of miRNA in FFPE tumour samples exhibiting degraded mRNA [Cervix samples miRNA]
Background: As degradation of formalin-fixed paraffin-embedded (FFPE) samples limits ability to expression profile, we explored factors predicting success for FFPE profiling and investigated an approach overcoming this limitation. Methods: Bladder (n=141, stored 3-8 years) and cervix (n=160, stored...
ORGANISM(S): Homo sapiens 
2012-07-03 | E-GEOD-39015 | biostudies-arrayexpress
TranscriptomicsInfluence of development and dietary phospholipid content and composition on intestinal transcriptome of Atlantic salmon (Salmo salar)
The inclusion of intact phospholipids in the diet is essential during larval development and can improve culture performance of many fish species. The effects of supplementation of dietary phospholipid from marine (krill) or plant (soy lecithin) sources were investigated in Atlantic salmon, Salmo sa...
ORGANISM(S): Salmo salar 
2015-08-20 | E-MTAB-3673 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of estradiol treated mouse fetal urogenital sinus mesenchyme cells
Developmental estrogen exposure causes permanent alterations to mouse prostate development. Fetal prostatic mesenchyme cells regulate epithelial cell proliferation and differentiation, and alterations to mesenchymal regulation of prostate epithelial cell proliferation and differentiation may lead t...
ORGANISM(S): Mus musculus 
2009-07-05 | E-GEOD-16854 | biostudies-arrayexpress
TranscriptomicsPaired whole blood human transcription profiles from children with severe malaria and mild malaria
Whole blood transcriptomes from a longitudinal study of 5 Malawian children who first present with severe Plasmodium falciparum malaria, and return in one month with mild malaria We used microarrays to identify transcripts that were associated with each clinical presentation. A blood sample was tak...
ORGANISM(S): Homo sapiens 
2012-01-11 | E-GEOD-33811 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Picea glauca xylem and phloem
In this experiment we compared the transcriptomes of xylem and phloem.
ORGANISM(S): Picea glauca 
2009-03-04 | E-MEXP-1489 | biostudies-arrayexpress
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