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MetabolomicsMulti-omics integration reveals Yu-Xue-Bi tablets attenuate rheumatoid arthritis via metabolic reprogramming-mediated Piezo1 suppression

As a systemic chronic inflammatory disease, Rheumatoid arthritis (RA) is characterized by progressive inflammation, bone and cartilage destruction, leading to significant disability, reduced lifespan, and increased mortality. The clinical use of conventional medications including nonsteroidal ant...

2026-01-24 | MTBLS13760 | MetaboLights
UnknownHippocampal PPARδ Overexpression or Activation Represses Stress-Induced Depressive Behaviors and Enhances Neurogenesis.
Not available
S-EPMC4772271 | biostudies-literature
TranscriptomicsTranscriptional profile comparison of M. tuberculosis PDIM spontaneous mutants
Transcriptional profile comparison among PDIM positive and negative isolates. Standard in vitro exponential phase cultures of M. tuberculosis H37Rv ATCC27294 were plated on 7H11 plates. Individual colonies were sub-cultured in 7H9 broth and metabolically labeled with [14C] propionic acid. The apolar...
ORGANISM(S): Mycobacterium tuberculosis 
2010-05-16 | E-GEOD-17234 | biostudies-arrayexpress
ProteomicsC. elegans as a model for inter-individual variation in metabolism
Fox BW, Ponomarova O, Lee YU, Zhang G, Giese EG, Walker M, Roberto NM, Na H, Reis-Rodrigues P, Curtis BJ, Kolodziej AR, Crombie TA, Zdraljevic S, Yilmaz LS, Andersen EC, Schroeder FC, Walhout AJM (2022) C. elegans as a model for inter-individual variation in metabolism
ORGANISM(S): Caenorhabditis Elegans (ncbitaxon:6239) 
2021-07-13 | MSV000087810 | MassIVE
MetabolomicsL-fucose and fucoidan alleviate high-salt diet-promoted acute inflammation

Excessive salt intake is a widespread health issue observed in almost every country around the world. A high salt diet (HSD) has a strong correlation with numerous diseases, including hypertension, chronic kidney disease and autoimmune disorders. However, the mechanisms underlying HSD-promotion o...

2024-02-21 | MTBLS9134 | MetaboLights
UnknownMeisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy.
Not available
S-EPMC12140364 | biostudies-literature
UnknownUtility of viscoelastic hemostatic assay to guide hemostatic resuscitation in trauma patients: a systematic review.
Not available
S-EPMC9472418 | biostudies-literature
UnknownPrognostic Score-based Clinical Factors and Metabolism-related Biomarkers for Predicting the Progression of Hepatocellular Carcinoma.
Not available
S-EPMC7518001 | biostudies-literature
TranscriptomicsTranscriptomics of Bacillus thuringiensis Strain CT-43.
We investigated the gene expression and metabolic regulatory mechanisms associated with the high-level accumulation of ICPs by performing the transcriptomics analysis of B. thuringiensis strain CT-43, using Illumina high throughout sequencing (RNA-seq) technique. The bacterial cells were collected a...
ORGANISM(S): Bacillus thuringiensis 
2013-04-17 | E-GEOD-39479 | biostudies-arrayexpress
UnknownA Novel Hydroxamate-Based Compound WMJ-J-09 Causes Head and Neck Squamous Cell Carcinoma Cell Death via LKB1-AMPK-p38MAPK-p63-Survivin Cascade.
Not available
S-EPMC5837967 | biostudies-literature
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