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MetabolomicsPu-erh tea and theabrownin ameliorate metabolic syndrome in mice via potential microbiota-gut-liver-brain interactions
Metabolic syndrome (MS) is a common metabolic disorder characterized by obesity, insulin resistance, cardiovascular disease and gut microbiota dysbiosis. Pu-erh tea and its ingredient theabrownin have known functions on the reduction of body weight gain and fat accumulation. However, few studies sys...
2024-09-25 | MTBLS2594 | MetaboLights
UnknownUSP22 deficiency leads to myeloid leukemia upon oncogenic Kras activation through a PU.1-dependent mechanism.
Not available
S-EPMC6071563 | biostudies-literature
TranscriptomicsConsequences of GATA1 expression in Gata1- G1ME Murine Megakaryocyte/Erythrocyte Progenitor Cell Line
G1ME cells are GATA1-deficient murine bipotential megakaryocyte/erythrocyte progenitor cells derived from Gata1-negative murine ES cells. In order to assess the impact of GATA1 on gene regulation and cell differentiation, an expression construct was used to transiently produce high levels of GATA1....
ORGANISM(S): Mus musculus 
2009-06-10 | E-GEOD-14980 | biostudies-arrayexpress
UnknownTranscriptional regulation of the proto-oncogene Zfp521 by SPI1 (PU.1) and HOXC13.
Not available
S-EPMC5073027 | biostudies-literature
UnknownUnraveling the flavor formation process of mellow and thick-type ripened Pu-erh tea through non-targeted metabolomics and metagenomics.
Not available
S-EPMC12002954 | biostudies-literature
MetabolomicsMechanism of interventional effect and targets of Zhuyu Pill in regulating and suppressing colitis and cholestasis

Zhuyu pill (ZYP) is a traditional Chinese medicine prescription composed of two drugs, Coptis chinensis Franch. and Tetradium ruticarpum (A. Jussieu) T. G. Hartley, and is commonly used in the clinical treatment of diseases of the digestive system. However, the mechanism underly...

2022-11-02 | MTBLS4980 | MetaboLights
UnknownCircular RNA circSnx5 Controls Immunogenicity of Dendritic Cells through the miR-544/SOCS1 Axis and PU.1 Activity Regulation.
Not available
S-EPMC7646215 | biostudies-literature
UnknownAnnexin A2 regulates unfolded protein response via IRE1-XBP1 axis in macrophages during P. aeruginosa infection.
Not available
S-EPMC8669835 | biostudies-literature
GenomicsCreation of an anti-inflammatory GR cistrome by TLR4 signaling
An unresolved molecular paradox is how the glucocorticoid receptor (GR) activates some genes while potently repressing others. We carried out genome-wide localization and expression profiling experiments in primary bone marrow-derived mouse macrophages treated with Dexamethasone in the presence or a...
ORGANISM(S): Mus musculus 
2012-12-04 | E-GEOD-31796 | biostudies-arrayexpress
UnknownA novel resin cement to improve bonding interface durability.
Not available
S-EPMC9415027 | biostudies-literature
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