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ProteomicsIsobaric labeling strategy utilizing 4-plex N, N-dimethyl leucine (DiLeu) tags reveals proteomic changes induced by chemotherapy-related neurotoxicity in cerebrospinal fluid of children
Using mass spectrometry for protein identification and quantification in cerebrospinal fluid (CSF) is at the forefront of research efforts to explore the pathophysiology biomarkers for the early diagnosis and prognosis of neurologic disorders. Here we implemented 4-plex N, N-dimethyl leucine (DiLeu)...
ORGANISM(S): Homo sapiens (Human) 
2020-07-02 | PXD017415 | Pride
Leukemia Isobaric labeling Csf proteomics 
ProteomicsIn-depth site-specific O-glycosylation analysis of glycoproteins and endogenous peptides in cerebrospinal fluid (CSF) from healthy individual mild cognitive impairment (MCI) and Alzheimer disease (AD) patients
Site-specific O-glycoproteome mapping in complex biological system provides molecular basis for understanding the structure-function relationships of glycoproteins and their roles in physiological and pathological processes. Previous O-glycoproteome analysis in cerebrospinal fluid (CSF) focused on s...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-04-05 | MSV000087160 | MassIVE
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