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TranscriptomicsA gp130-induced Src/Yes-YAP Cascade Links Inflammation to Regeneration in the Mammalian Intestine
gp130Act cDNA was PCR-amplified and inserted into a plasmid containing the 12.4-kb Villin promoter. The 15.7-kb expression cassette was excised by PmeI digestion, purified, and injected into fertilized C57BL/6 oocytes to obtain founder mice, two of which transmitted the gp130Act transgene. Small int...
ORGANISM(S): Mus musculus 
2015-02-21 | E-MTAB-2400 | biostudies-arrayexpress
ProteomicsTargeted mass spectrometry enables multiplexed quantification of immunomodulatory proteins in clinical biospecimens
Immunotherapies are revolutionizing cancer care, producing durable responses and potentially cures in a subset of patients. However, response rates are low for most tumors, grade 3/4 toxicities are not uncommon, and our current understanding of tumor immunobiology is incomplete. While hundreds of im...
ORGANISM(S): Homo Sapiens 
2022-02-28 | PXD029167 | panorama
UnknownGenome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer.
Not available
S-EPMC2839871 | biostudies-literature
UnknownA genome-wide association study identifies pancreatic cancer susceptibility loci on chromosomes 13q22.1, 1q32.1 and 5p15.33.
Not available
S-EPMC2853179 | biostudies-literature
UnknownGlobal Burden of Cardiovascular Diseases and Risk Factors, 1990-2019: Update From the GBD 2019 Study.
Not available
S-EPMC7755038 | biostudies-literature
UnknownBenchmarking cell type and gene set annotation by large language models with AnnDictionary.
Not available
S-EPMC12569162 | biostudies-literature
UnknownFemale chromosome X mosaicism is age-related and preferentially affects the inactivated X chromosome.
Not available
S-EPMC4909985 | biostudies-literature
UnknownImputation and subset-based association analysis across different cancer types identifies multiple independent risk loci in the TERT-CLPTM1L region on chromosome 5p15.33.
Not available
S-EPMC4240198 | biostudies-literature
UnknownNational-level and state-level prevalence of overweight and obesity among children, adolescents, and adults in the USA, 1990-2021, and forecasts up to 2050.
Not available
S-EPMC11694015 | biostudies-literature
UnknownMultiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer.
Not available
S-EPMC3670748 | biostudies-literature
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