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MetabolomicsCD73 inhibitor AB680 suppresses glioblastoma in mice by inhibiting purine metabolism and promoting P2RY12<sup>+</sup> microglia transformation.
CD73 (ecto-5'-nucleotidase) is a metabolic immune checkpoint that dephosphorylates AMP to produce adenosine. Adenosine plays a pivotal role in immunosuppressive tumor microenvironment (TME) through adenosine receptors expressed on various immune cells. AB680, a specific CD73 inhibitor, is currently ...
2025-08-04 | MTBLS11084 | MetaboLights
ProteomicsProteomic analysis reveals the mechanism of different environmental stresses-induced tolerance of Pseudomonas aeruginosa PAO1 to the monochloramine disinfection
Although drinking water disinfection has proved to be an effective strategy to eliminate most waterborne pathogens, bacterial pathogens can still show disinfection tolerance in drinking water distribution systems (DWDSs), posing a great threat to drinking water safety and human health. Despite stres...
ORGANISM(S): Pseudomonas Aeruginosa Pao1 
2020-10-10 | PXD021907 |
UnknownExtracting the femtometer structure of strange baryons using the vacuum polarization effect.
Not available
S-EPMC11470094 | biostudies-literature
UnknownProbing CP symmetry and weak phases with entangled double-strange baryons.
Not available
S-EPMC9159954 | biostudies-literature
UnknownGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).
Not available
S-EPMC4835977 | biostudies-literature
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