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MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
MetabolomicsClinical efficacy of Yiqi Yangxue formula on knee osteoarthritis and unraveling therapeutic mechanism through plasma metabolites in rats.

OBJECTIVE: To observe the clinical efficacy and safety of Yiqi Yangxue formula (YQYXF) on knee osteoarthritis (KOA), and to explore the underlying therapeutic mechanism of YQYXF through endogenous differential metabolites and their related metabolic pathways.

METHOD...

2024-03-25 | MTBLS5667 | MetaboLights
ProteomicsQuantitative proteomic analysis reveals the expression of various proteins in mice during the tumor treatment
Based on the gene ontology (GO) results, we found that proteins associated with responses or processes related to stimulus, immune system, signalling, cell killing, and antioxidant activity were more up-regulated after MiBaMc treatment. In contrast, proteins that related to cell integrity and cell g...
ORGANISM(S): Mus Musculus 
2022-09-28 | PXD037069 |
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