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TranscriptomicsExpression Data From HCMV-Infected Human Monocytes: Role of EGFR
Human cytomegalovirus (HCMV) induces pro-inflammatory monocytes following infection and we have evidence that EGFR is a key mediator in this early activation. To begin to address how this signalling pathway is responsible for the rapid activation of infected monocytes, we examined the role this pat...
ORGANISM(S): Homo sapiens 
2009-09-03 | E-GEOD-17948 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HCMV-Infected monocytes study 2
Human cytomegalovirus induces a pro-inflammatory monocyte following infection. To begin to address how HCMV induces these rapid changes in infected monocytes, we examined the transcriptome of infected monocytes. Global transcriptional profiling using cDNA microarrays revealed a significant number ...
ORGANISM(S): Homo sapiens 
2008-06-20 | E-GEOD-11408 | biostudies-arrayexpress
TranscriptomicsThe role of integrins in human cytomegalovirus (HCMV)-infected monocytes.
We have established that human cytomegalovirus (HCMV) infection modulates the biology of target primary blood monocytes, allowing HCMV to use monocytes as 'vehicles' for its systemic spread. HCMV infection of monocytes results in rapid induction of PI(3)K and NF-kB activity. Integrins, which are u...
ORGANISM(S): Homo sapiens 
2010-10-31 | E-GEOD-24238 | biostudies-arrayexpress
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