Sort   by:  
 Page size 
ProteomicsProteome landscape of epithelial to mesenchymal transition (EMT) of retinal pigment epithelium shares commonalities with malignancy-associated EMT
Retinal pigment epithelium (RPE) stress and injury often leads to epithelial to mesenchymal transition (EMT), in which RPE cells lose its cobblestone morphology and acquire more motile and spindle-shaped fibroblast phenotype. RPE dysfunction due to acquired EMT phenotype have been implicated in a ...
ORGANISM(S): Homo sapiens (Human) 
2021-09-21 | PXD019600 | Pride
Emt Rpe Mass spectrometry and vision research Proteomics 
TranscriptomicsConditional knockdown of DNA methyltransferase-1 (Dnmt1) reveals a key role of retinal pigment epithelium integrity in photoreceptor outer segment morphogenesis
To explore the epigenetic contribution to retinal development, we generated conditional knockout alleles of DNA methytransferase-1 (Dnmt1) mediated by Rx-Cre in mice. The results demonstrate a unique function of DNMT1-mediated DNA methylation in controlling RPE apicobasal polarity and neural retina...
ORGANISM(S): Mus musculus 
2013-01-31 | E-GEOD-43951 | biostudies-arrayexpress
Sort   by:  
 Page size