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TranscriptomicsDLD1
DLD1 is an APC mut, KRAS mut, P53 mut CRC cell line. PROX1 transcription factor, target of Wnt pathway in CRC, is our protein of interest.DLD1 cells are PROX1 negative. We overexpressed through lentiviral expression PROX1 protein or the empty vector psd44, through selection of the cells in puromycin...
ORGANISM(S): Homo Sapiens 
2014-09-18 | E-MTAB-2020 | biostudies-arrayexpress
TranscriptomicsSW480R
SW480R is an APC mut, KRAS mut, P53 mut CRC cell line. PROX1 transcription factor, target of Wnt pathway in CRC, is our protein of interest.SW480R cells are PROX1 positive. We suppressed through siRNA transfection the expression of PROX1 protein or non-targeting siRNA, using two different siRNA. Aft...
ORGANISM(S): Homo Sapiens 
2014-09-18 | E-MTAB-2021 | biostudies-arrayexpress
TranscriptomicsExpression profile of human lymphatic endothelial cells under static or oscillatory shear stress conditions in the presence or absence of FOXC2
Lymphatic valves are specialized units regularly distributed along collecting vessels that allow unidirectional forward propulsion of the lymph, and its efficient transport from tissues to the bloodstream. Lymphatic endothelial cells that cover lymphatic valve sinuses are subjected to complex flow p...
ORGANISM(S): Homo sapiens 
2015-11-09 | E-GEOD-60152 | biostudies-arrayexpress
GenomicsPROX1 ChIP-seq analysis of human colorectal cancer cells SW480R
We performed ChIP-seq data in SW480R cells. Pools of three independent ChIP experiments and input DNA were used for sequencing.
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-60390 | biostudies-arrayexpress
TranscriptomicsChIP-chip study aimed at the identification of the repertoire of FOXC2 binding sites affected by the loss of FOXC2 phosphorylation in primary human lymphatic endothelial cells (LECs)
Chromatin immunoprecipitation microarray (ChIP-chip) study using anti-Myc (9E10) antibodies and primary human lymphatic endothelial cells (LECs) transduced with recombinant adenoviruses expressing wild type or phosphorylation-deficient Myc-tagged FOXC2.
ORGANISM(S): Homo sapiens 
2013-07-13 | E-MTAB-596 | biostudies-arrayexpress
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