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ProteomicsEngineered immunomodulatory extracellular vesicles derived from epithelial cells acquire capacity for positive and negative T cell co-stimulation in cancer and autoimmunity.
Extracellular vesicles (EVs) are generated by all cells and systemic injection of allogenic EVs derived from epithelial or mesenchymal cells into humans and immunocompetent mice do not elicit any immune response despite the presence of ~1,200 proteins. Nevertheless, EVs from immune cells are purport...
ORGANISM(S): Homo sapiens (Human) 
2025-05-08 | PXD044115 | Pride
T cell function Cancer Extracellular vesicles Immune regulation 
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