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TranscriptomicsTranscription profiling of Wistar rat preconditioned hearts either perfused alone or subjected to ischemia and then reperfused
Isolated perfused rat hearts exposed to isoflurane or ischemic preconditioning, a subgroup followed by 40 minutes of ischemia and 3 hours of reperfusion. Exact protocol available from the authors.
ORGANISM(S): Rattus norvegicus 
2007-11-01 | E-GEOD-1616 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human atrial tissue from patients undergoing coronary artery bypass graft surgery to determine the effect of anesthesia on gene expression
Anesthetic gases elicit organ protection in patients undergoing coronary artery bypass graft (CABG) surgery. This study aimed at identifying myocardial transcriptional phenotypes and anesthetic-induced changes in gene expression to predict cardiovascular biomarkers and cardiac function after off-pu...
ORGANISM(S): Homo sapiens 
2008-11-22 | E-GEOD-4386 | biostudies-arrayexpress
TranscriptomicsRemote ischemic preconditioning in on-pump coronary artery bypass graft surgery
In this placebo-controlled randomized controlled trial, we tested whether remote ischemic preconditioning (RIPC) elicited by four 5-minute cycles of 300 mmHg of cuff inflation/deflation of the lower limb would reduce myocardial necrosis in isoflurane-anesthetized patients undergoing on-pump coronary...
ORGANISM(S): Homo sapiens 
2012-10-12 | E-GEOD-29396 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of rat hearts isolated perfused and exposed to doxorubicin
We used microarrays to detail transcriptional changes in the rat heart in response to doxorubicin, a chemotherapeutic drug known to induce cardiac disfunction/heart failure Experiment Overall Design: Langendorff perfusion of isolated hearts with/without doxorubicin
ORGANISM(S): Rattus norvegicus 
2009-01-14 | E-GEOD-12260 | biostudies-arrayexpress
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