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TranscriptomicsComparison of rat thoracic duct to vena cava
While blood vessels have muscular walls that undergo tonic contractions to alter vascular resistance and, thus, control blood flow, lymphatics at the level of the collecting vessels and higher have muscular walls capable of rapid phasic contractions that generate lymph flow in addition to tonic cont...
ORGANISM(S): Rattus norvegicus 
2010-05-15 | E-GEOD-7221 | biostudies-arrayexpress
TranscriptomicsThe effects of oxygen treatments on angiogenesis and lymphangiogenesis in mouse embryoid bodies
This study investigates the processes of angiogenesis and lymphangiogenesis in an in vitro mouse Embryoid Body (EB) model while maintaining as closely as possible an in vivo environment that is observed in human and murine placental development. Several studies have documented that human placental d...
ORGANISM(S): Mus musculus 
2012-08-11 | E-GEOD-17613 | biostudies-arrayexpress
TranscriptomicsCharacterization of the transcriptional heterogeneity present within the rat lymphatic and blood vasculatures
The goal and objective of this study was to identify the transcriptional profiles differentiating the artery, vein, and lymphatic lineages in the adult rat vasculature with particular emphasis on the unique elements of the collecting lymphatic vessel transcriptome. A 2 x 3 experimental design was ut...
ORGANISM(S): Rattus norvegicus 
2012-06-22 | E-GEOD-17015 | biostudies-arrayexpress
TranscriptomicsEvaluation of the effects of shear stress on human dermal microvascular blood and lymphatic endothelial cells
The lymphatic system removes fluid from the interstitial space and returns it to the blood with a tremendous capacity: during inflammation, lymph flow rates can increase dramatically; however, during chronic lymphedema, there is little or no flow. The ability of lymphatic endothelium to sense and ac...
ORGANISM(S): Homo sapiens 
2009-11-30 | E-GEOD-8852 | biostudies-arrayexpress
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