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TranscriptomicsExpression profiling of FOXK2 depletion by siRNA
Expression profiling was done of FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line (which stably expresses FOXK2).
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3106 | biostudies-arrayexpress
TranscriptomicsExpression profiling of exposure to phorbol myristate acetate - PMA and FOXK2 depletion with siRNA
Expression profiling was done of exposure to phorbol myristate acetate -PMA and FOXK2 depletion by siRNA transfection. This was done on the human osteosarcoma U2OS cell line which stably expresses FOXK2. PMA is an inducer of AP1 activity.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3107 | biostudies-arrayexpress
TranscriptomicsFOXK2 ChIP-chip
Chromatin immunoprecipitation of FOXK2 (tagged with Flag and His tags) in U2OS cells detected by Affymetrix human promoter array 1.0R.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3116 | biostudies-arrayexpress
MetabolomicsGrowth control of the eukaryote cell: a systems biology study in yeast
Metabolic control analysis is being exploited in a systems biology study of the eukaryotic cell. Using chemostat culture, we have measured the impact of changes in flux (growth rate) on the transcriptome, proteome, endometabolome and exometabolome of the yeast Saccharomyces cerevisiae. Each function...
2012-04-19 | MTBLS8 | MetaboLights
TranscriptomicsTranscription profiling of Arabidopsis stem, leaf and hypocotyl tissue undergoing varying amounts of secondary cell wall synthesis
The aim of this experiment was to understand secondary cell wall formation as it is a major constituent of wood and plant fibres. To identify potential novel genes involved in this process, data has been generated from Arabidopsis stem, leaf and hypocotyl tissue undergoing varying amounts of seconda...
ORGANISM(S): Arabidopsis thaliana 
2006-01-01 | E-MEXP-265 | biostudies-arrayexpress
TranscriptomicsFOXK2 promotes AP-1 mediated transcriptional regulation - transcription profiling FOXK2 induction
Transcription profiling of FOXK2 expression in HeLa cells from a stably integrated doxycyline-inducible EGFP-FOXK2 expression construct.
ORGANISM(S): Homo sapiens 
2011-11-03 | E-MEXP-3040 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of wound samples from rats treated with the 5alpha-reductase inhibitor MK-434
The present study aimed to delineate the central mechanisms by which androgens delay wound repair. Blocking the conversion of testosterone to 5alpha-dihydrotestosterone (DHT) by 5alpha-reductase limits its ability to impair skin wound healing, suggesting that DHT is a more potent inhibitor of repair...
ORGANISM(S): Rattus norvegicus 
2009-02-20 | E-MEXP-1232 | biostudies-arrayexpress
TranscriptomicsTranscriptome Analysis of Preinvasive and Invasive Early Squamous Carcinoma in Archival Laser Microdissected Samples
Preinvasive squamous cell cancer (PSCC) are local transformations of bronchial epithelia that are frequently observed in current or former smokers. Their different grades and sizes suggest a continuum of dysplastic change with increasing severity, which may culminate in invasive squamous cell carcin...
ORGANISM(S): Homo sapiens 
2017-06-09 | E-MTAB-3950 | biostudies-arrayexpress
TranscriptomicsAPE1 knock-in
APE1/Ref-1 protects cells from oxidative stress by acting as a central enzyme in base excision repair pathways of DNA lesions and through its independent activity as a redox transcriptional co-activator. To dissect between redox- and DNA-repair-mediated effects, here we performed transcription profi...
ORGANISM(S): Homo sapiens 
2011-10-01 | E-MEXP-2941 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of bovine nucleus pulposus, carticular cartilage and annulus fibrosus cells to further determine expression in normal and degenerate human intervertebral disc
The aim of this transcription profiling study was to identify novel genes that could be used to distinguish bovine Nucleus pulposus (NP) cells from articular cartilage (AC) and annulus fibrosus (AF) cells and to further determine their expression in normal and degenerate human intervertebral disc (I...
ORGANISM(S): Bos taurus 
2010-03-05 | E-MEXP-2291 | biostudies-arrayexpress
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