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TranscriptomicsGene expression profiling in a VRK1 R358X homozygote patient
VRK1 mutations in humans cause a severe neuronal phenotype includung spinal muscular atrophy (SMA) and microcephaly. To study the effect of VRK1 R358X mutation on global gene expression in a homozygote human patient, an expression array was performed using EBV-trasformed B cells from the patient and...
ORGANISM(S): Homo sapiens 
2015-02-19 | E-GEOD-66061 | biostudies-arrayexpress
TranscriptomicsExpression data from HeLa cells overexpressing AK125393
Expression of RAD51, a crucial player in homologous recombination (HR) and DNA double-strand break (DSB) repair, is dysregulated in human tumors, and can contribute to genomic instability and tumor progression. To further understand RAD51 regulation we functionally characterized a long non-coding (l...
ORGANISM(S): Homo sapiens 
2015-02-19 | E-GEOD-66062 | biostudies-arrayexpress
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