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TranscriptomicsLow-density miRNA microarray of induced mouse myeloid-derived suppressor cell
Myeloid-derived suppressor cells (MDSCs) are one of the main cell populations that negatively regulate immune responses. However, the mechanism underlying the differentiation and expansion of MDSCs remains unclear. Employing a low-density miRNA microarray and a TaqMan probe-based qRT-PCR assay, we ...
ORGANISM(S): Mus musculus 
2014-03-11 | E-GEOD-50914 | biostudies-arrayexpress
TranscriptomicsDifferential Expression of MicroRNAs in Mouse Liver under Aberrant Energy Metabolic Status
Despite years of effort, exact pathogenesis of non-alcoholic fatty liver disease (NAFLD) remains obscure. To gain an insight into the regulatory roles of microRNAs (miRNAs) in aberrant energy metabolic status and pathogenesis of NAFLD, we analyzed the expression of miRNAs in livers of ob/ob mice, st...
ORGANISM(S): Mus musculus 
2010-05-18 | E-GEOD-13840 | biostudies-arrayexpress
UnknownAn Ebola virus-encoded microRNA-like fragment serves as a biomarker for early diagnosis of Ebola virus disease.
Not available
S-EPMC4783470 | biostudies-literature
TranscriptomicsExpression data comparing the effect of IKK2 KO on a KRAS mouse model
Given that the NF-κB pathway plays an important role in tumor development and that IKK2 is the seminal kinase responsible for NF-κB pathway activation, we were particularly interested in exploring the therapeutic potential of IKK2 inhibition in non-small cell lung cancers. We crossed IKK2fl/fl and K...
ORGANISM(S): Mus musculus 
2011-12-15 | E-GEOD-30049 | biostudies-arrayexpress
UnknownUCP2-induced hypoxia promotes lipid accumulation and tubulointerstitial fibrosis during ischemic kidney injury.
Not available
S-EPMC6957698 | biostudies-literature
UnknownSodium-glucose cotransporter 2 inhibition suppresses HIF-1α-mediated metabolic switch from lipid oxidation to glycolysis in kidney tubule cells of diabetic mice.
Not available
S-EPMC7242894 | biostudies-literature
UnknownCold-activated brown fat-derived extracellular vesicle-miR-378a-3p stimulates hepatic gluconeogenesis in male mice.
Not available
S-EPMC10482845 | biostudies-literature
TranscriptomicsPostia placenta MAD-698 gene expression in different media
Transscript profiles of Postia placenta grown on different substrates were analyszed. Array design was based on the DoE's Joint Genome Institute's gene models for P. placenta version 1. The research goal is to identtify genes essential for cellulose depolymerization. Keywords: Culture condition com...
ORGANISM(S): Postia placenta 
2010-05-14 | E-GEOD-12540 | biostudies-arrayexpress
TranscriptomicsExpression data of transduced mouse glioblastomas
Transgenic GFAP-, NES-, and SYN- CRE mice were injected with a lenti-viral construct containing a floxed RFP directly upstream of a cassette containing si-p53, GFP, and mutant HRAS. Tumors arising from the various CRE tissue specific promoters and differing injections sites were compared to normal h...
ORGANISM(S): Mus musculus 
2012-10-18 | E-GEOD-35917 | biostudies-arrayexpress
ProteomicsThe Glomerulus Multi-Omics Analysis Provides Deeper Insights into Diabetic Nephropathy
Diabetic nephropathy (DN) is the leading cause of end-stage renal disease (ESRD), however, the detail mechanisms remain unclear. Here, we integrated the transcriptomics and proteomics profiles of glomeruli isolated from 50 biopsy-proven DN patients and 25 controls to explore the new discoveries unde...
ORGANISM(S): Homo Sapiens 
2023-03-06 | PXD040617 |
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