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MetabolomicsLsr2, a novel cyclic di-GMP receptor, regulate the synthesis of keto-mycolic acid and control biofilm formation in mycobacteria

Cyclic di-GMP (c-di-GMP) is a well-known second messenger that plays a key role in many physiological processes in bacteria. The synthesis of lipids is essential for bacterial biofilm formation. However, whether c-di-GMP signaling modulates the synthesis of lipid and further regulates biofilm for...

2023-12-12 | MTBLS7053 | MetaboLights
ProteomicsA WYL transcription factor regulates Lactiplantibacillus plantarum intestinal colonization via perceiving c-di-GMP
The WYL transcription factor (LP_RS00300) is a c-di-GMP effector in L. plantarum WCFS1. LP_RS00300 binds to a special motif within the coding sequence, impeding the transcriptional elongation of LP_RS05345 and LP_RS05225, which encode mucus binding proteins (MucBPs). The perception of c-di-GMP by th...
ORGANISM(S): Lactobacillus plantarum WCFS1 Bacteria 
2025-02-14 | PXD053948 | Pride
C-di-gmp receptor Wyl transcription factor Lactiplantibacillus plantarum 
TranscriptomicsTranscription profiling of mouse Perk wild-type and knockout liver perfused without or with 2,5-di-tert-butylhydroquinone
In eukaryotes, regulation of mRNA translation enables a fast, localized and finely tuned expression of gene products. Within the translation process, the first stage of translation initiation is most rigorously modulated by the actions of eukaryotic initiation factors (eIFs) and their associated pr...
ORGANISM(S): Mus musculus 
2009-11-23 | E-GEOD-11684 | biostudies-arrayexpress
TranscriptomicsAltered gene expression in the small intestine of IE-Cpr-null mice
The NADPH-cytochrome P450 reductase (CPR) is essential for the functioning of microsomal cytochrome P450 (P450) monoxygenases. The biological functions of the CPR-dependent enzymes in the intestine are not known, despite the vast knowledge available on the biochemical properties of the various oxyge...
ORGANISM(S): Mus musculus 
2012-04-10 | E-GEOD-35293 | biostudies-arrayexpress
UnknownIdentification of a Novel Di-D-Fructofuranose 1,2':2,3' Dianhydride (DFA III) Hydrolysis Enzyme from Arthrobacter aurescens SK8.001.
Not available
S-EPMC4640833 | biostudies-literature
UnknownAncient DNA reveals genetic connections between early Di-Qiang and Han Chinese.
Not available
S-EPMC5716020 | biostudies-literature
UnknownSystematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1.
Not available
S-EPMC7733949 | biostudies-literature
ProteomicsD. vulgaris WT & DsrC mutants -- respiration & fermentation
diDO-IPTL proteomics data of Desulfovibrio vulgaris Hildenborough wild type and two DsrC point mutants (IPFG07 & IPFG09) under sulfate-reducing (respiration) and fermentative growth (late-exponential phase)
ORGANISM(S): Desulfovibrio Vulgaris Str. Hildenborough (ncbitaxon:882) 
2022-10-27 | MSV000090596 | MassIVE
UnknownDarR, a TetR-like transcriptional factor, is a cyclic di-AMP-responsive repressor in Mycobacterium smegmatis.
Not available
S-EPMC3561532 | biostudies-literature
UnknownCyclic di-GMP modulates sessile-motile phenotypes and virulence in Dickeya oryzae via two PilZ domain receptors.
Not available
S-EPMC9104268 | biostudies-literature
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