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MetabolomicsSystem Xc- exacerbates metabolic stress under glucose depletion in oral squamous cell carcinoma

OBJECTIVE: Emerging evidence suggests that glucose depletion (GD)-induced cell death depends on system Xc-, a glutamate/cystine antiporter extensively studied in ferroptosis. However, the underlying mechanism remains debated. Our study confirmed the correlation between system Xc...

2024-01-16 | MTBLS5358 | MetaboLights
ProteomicsEarly Proteomic and Metabolomic Signatures in Diabetes Associated with Progression to Diabetic Retinopathy Over 1–2 Years
In this study, we leveraged 15 paired plasma samples collected from the same individuals who exhibited rapid progression from DM to DR within 1-2 years and conducted integrated proteomic and metabolomic analyses to investigate molecular changes associated with disease progression. Key proteins were ...
ORGANISM(S): Homo Sapiens 
PXD078538 |
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