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ProteomicsSuper-SILAC analysis of human lung primary tumor-derived xenografts LC-MS/MS
Non-small cell lung cancer (NSCLC) accounts for 85% of lung cancers, and is subdived into 2 major histological subtypes: adenocacinoma (ADC) and squamous cell carcinoma (SCC). Super-SILAC methodology was used to facilitate the quantitative comparisons of human primary tumor-derived xenograft proteom...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-07-02 | MSV000079881 | MassIVE
TranscriptomicsGene expression analysis of non-cerebellar portion of Gb5-deficient mice brain
Gb5 is a divergent, evolutionarily-conserved, member of the heterotrimeric G protein b subunit family that is expressed principally in brain and neuronal tissue. Among Gb isoforms, Gb5 is unique in its ability to heterodimerize with members of the R7 subfamily of the regulator of G protein signalin...
ORGANISM(S): Mus musculus 
2011-09-12 | E-GEOD-29082 | biostudies-arrayexpress
TranscriptomicsCerebellar gene expression analysis of Gb5-deficient mice
Gb5 is a divergent, evolutionarily-conserved, member of the heterotrimeric G protein b subunit family that is expressed principally in brain and neuronal tissue. Among Gb isoforms, Gb5 is unique in its ability to heterodimerize with members of the R7 subfamily of the regulator of G protein signalin...
ORGANISM(S): Mus musculus 
2011-09-12 | E-GEOD-29081 | biostudies-arrayexpress
TranscriptomicsKnockout of heterotrimeric signaling G protein beta5 impaires brain development and causes severe neurologic dysfunction in mice
This SuperSeries is composed of the following subset Series: GSE29081: Cerebellar gene expression analysis of Gb5-deficient mice GSE29082: Gene expression analysis of non-cerebellar portion of Gb5-deficient mice brain Refer to individual Series
ORGANISM(S): Mus musculus 
2011-09-12 | E-GEOD-29083 | biostudies-arrayexpress
ProteomicsImmobilization of Ce(IV)-substituted polyoxometalate on ethylenediamine-functionalized graphene oxide for the isolation of intact phosphoproteins
Phosphorylation of protein plays a key role in the regulation of many biological processes. Herein, a simple approach is developed by immobilization of Ce(IV)-substituted polyoxometalate on ethylenediamine-functionalized graphene oxide (CeEGO) as adsorbent for selective isolation of intact phosphop...
ORGANISM(S): Homo Sapiens 
2018-07-20 | PXD010524 |
ProteomicsAlternative Splicing of VRF1 Acts as a Molecular Switch to Regulate Stress-Induced Early Flowering
The phosphorylation mass spectrometry proteomics data in vitro
ORGANISM(S): Arabidopsis Thaliana 
2024-09-30 | PXD056388 |
ProteomicsMeasurement of site-specific H2O2-sensitivity and identification of sulfenic acid modification of CLOCK cysteines
In vitro H2O2-sensitivity of CLOCK cysteines was measured with a quantitative chemoproteomic approach termed as QTRP (Quantitative Thiol Reactivity Profiling) as previously reported. In brief, 5 μg of recombinant CLOCK proteins were reduced with 1 mM DTT for 30 min at room temperature. After reactio...
ORGANISM(S): Homo Sapiens Mus Musculus 
2019-08-31 | PXD015266 |
Proteomicsmouse liver concatenated tandem array of consensus TF response elements (catTFRE) with H2O2
a pull-down assay using a concatenated tandem array of consensus TF response elements (catTFRE) to trap the TFs expressed in mouse livers following treatment with or without H2O2
ORGANISM(S): Mus Musculus 
2019-08-31 | PXD015265 |
ProteomicsA Pandas complex adapted for piRNA-guided transposon silencing and heterochromatin formation
dNxf2 directly interacts with dNxf1 to compete with its binding to NPC
ORGANISM(S): Drosophila Melanogaster 
2019-08-01 | PXD014884 |
ProteomicsA Pandas complex adapted for piRNA-guided transposon silencing and heterochromatin formation, Panx-IP-MS
The repression of transposons by the Piwi-interacting RNA (piRNA) pathway is essential to protect animal germ cells. In Drosophila ovaries, Panoramix (Panx) enforces transcriptional silencing by binding to the target-engaged Piwi-piRNA complex, although the precise mechanisms by which this occurs re...
ORGANISM(S): Drosophila Melanogaster 
2019-08-06 | PXD014926 |
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