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MetabolomicsExtracellular-acidosis restricts one-carbon metabolism and preserves T cell stemness
The accumulation of acidic metabolic waste products within the tumor microenvironment profoundly inhibits effector functions of tumor-infiltrating lymphocytes (TILs). However, it is unclear whether extracellular-acidosis impacts T cell metabolic fitness and differentiation status. Here, we surprisin...
2023-01-17 | MTBLS6661 | MetaboLights
ProteomicsAcross-cancer immune responses induced by nanovaccines or microvaccines to prevent different cancers and cancer metastasis
Cancer vaccines, reassembled from whole tumor tissue components, were applied to demonstrate the across-cancer immune responses, thanks to inducing pan-clones T cells immune responses. It is demonstrated that across-cancer immune responses among different types of cancers exist and can be induced by...
ORGANISM(S): Mus Musculus 
PXD037688 |
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