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MetabolomicsDiagnostic Potential of Plasma IgG N-glycans in Discriminating Thyroid Cancer from Benign Thyroid Nodules and Healthy Controls

BACKGROUND: Novel biomarkers are urgently needed to distinguish between benign and malignant thyroid nodules and detect thyroid cancer in the early stage. The associations between serum IgG N-glycosylation and thyroid cancer risk have been revealed. We aimed to explore the potent...

2021-09-01 | MTBLS2935 | MetaboLights
TranscriptomicsHigh salt primes a specific activation state of macrophages, M(Na)
Purpose: Investigate effects of high salt on human macrophage activation Methods: Human monocytes-derived macrophages were treated by additional 51mM NaCl for 24 hours (NaCl groups) or not (Control groups). mRNA profiles were generated by RNA-Seq, in triplicate, using Ion proton（Life tech). qRT–PCR ...
ORGANISM(S): Homo sapiens 
2015-09-23 | E-GEOD-68482 | biostudies-arrayexpress
ProteomicsAn automated intact glycopeptide enrichment method for serum site-specific N-glycoproteomic analysis
We developed an automated glycopeptide enrichment method for the analysis of serum site-specific N-glycoproteome. This automated method allowed for processing one sample within 20 min. It showed higher enrichment specificity, more intact glycopeptide identifications, and better quantitative reproduc...
ORGANISM(S): Homo Sapiens (human) 
2021-04-06 | PXD025151 | JPOST Repository
MetabolomicsMetabolite profiling of Arabidopsis mutants of enzymes of lower glycolysis
We have previously shown that in Arabidopsis the three enzymes of lower glycolysis phosphoglycerate mutase (PGAM), enolase and pyruvate kinase form a complex which play an important role in co-sub-cellar localization the mitochondria to the chloroplast. Given that their metabolites of these mutants,...
2022-10-10 | MTBLS4066 | MetaboLights
OtherThe N-cadherin interactome in primary cardiomyocytes
Low levels of Cdh2-BioID2 were expressed in mouse primary neonatal cardiomyocytes using an adenoviral expression system. Infected cells were treated with biotin for 24 hours before lysis. Biotinylated proteins were precipitated from lysates using streptavidin beads. Protein samples were in-gel tryps...
ORGANISM(S): Mus Musculus 
2019-01-23 | MSV000083356 | MassIVE
UnknownN-myc downstream-regulated gene 2, a novel estrogen-targeted gene, is involved in the regulation of Na+/K+-ATPase.
Not available
S-EPMC3173200 | biostudies-literature
ProteomicsInvestigation of the aging process of C. elegans using integrated quantitative proteomics and N-glycoproteomics
N-glycosylation, a highly diverse and abundant post-translational modification, critically regulates organismal aging. Leveraging the Caenorhabditis elegans (C. elegans) model, which exhibits distinctive N-glycosylation features including highly fucosylated core structures, bisecting β1,4-galactose,...
ORGANISM(S): Caenorhabditis elegans 
2026-09-14 | PXD067150 | Pride
Aging process Nanolc-esi-ms/ms N-glycosylation Caenorhabditis elegans 
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownRealizing a High-Performance Na-Storage Cathode by Tailoring Ultrasmall Na2FePO4F Nanoparticles with Facilitated Reaction Kinetics.
Not available
S-EPMC6662290 | biostudies-literature
UnknownSolvated Electron-Driven Stepwise ORR on Na-Metalated N-Rich Carbon Nitride for Efficient Photocatalytic H<sub>2</sub>O<sub>2</sub> Production.
Not available
S-EPMC12767047 | biostudies-literature
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