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ProteomicsProteomic of Chaihu-Shugan-San (CSS), Rou Gan, and Shu Gan treat chronic unpredictable mild stress (CUMS) rat with Tandem Mass Tags
Chaihu-Shugan-San (CSS) is a classical prescription used to treat depression. According to the traditional Chinese medicine (TCM) principle, the 2 decomposed recipes in CSS exert synergistic effects, including Shu Gan (stagnated Gan-Qi dispersion) and Rou Gan (pain alleviation). However, the specifi...
ORGANISM(S): Rattus norvegicus (Rat) 
2022-02-17 | PXD024436 | Pride
Chaihu-shugan-san Hippocampus Depression Proteomics Traditional chinese medicine 
UnknownDetection of Cistanches Herba (Rou Cong Rong) Medicinal Products Using Species-Specific Nucleotide Signatures.
Not available
S-EPMC6242781 | biostudies-literature
UnknownProteomics Study Reveals the Anti-Depressive Mechanisms and the Compatibility Advantage of Chaihu-Shugan-San in a Rat Model of Chronic Unpredictable Mild Stress.
Not available
S-EPMC8802092 | biostudies-literature
UnknownCoordinating interleukin-2 encoding circRNA with immunomodulatory lipid nanoparticles to potentiate cancer immunotherapy.
Not available
S-EPMC11864171 | biostudies-literature
UnknownInhibition of DCLK1 kinase reverses epithelial-mesenchymal transition and restores T-cell activity in pancreatic ductal adenocarcinoma.
Not available
S-EPMC8739467 | biostudies-literature
ProteomicsSpecific sDMA Modifications on the RGG/RG Motif of METTL14 Regulate Its Function in AML
Protein arginine methylations are crucial post-translational modifications (PTMs) in eukaryotes, playing a significant regulatory role in diverse biological processes. Different forms of arginine methylations are known to co-exist within densely modified arginine-rich protein regions. However, pinpo...
ORGANISM(S): Homo Sapiens 
PXD054570 |
UnknownTesting and linkage to HIV care in China: a cluster-randomised trial.
Not available
S-EPMC6639122 | biostudies-literature
ProteomicsPhenotypic heterogeneity analysis of APC-mutant colon cancer by proteomics and phosphoproteomics identifies RAI14 as a key prognostic determinant
Adenomatous polyposis coli (APC) is an important tumor suppressor and most directly related to the regulation of WNT/β-catenin signaling pathway. APC mutation has been identified as an early event in more than 80% of sporadic colorectal cancers (CRCs). However, obvious prognostic differences are obs...
ORGANISM(S): Homo Sapiens 
2022-11-10 | PXD038081 |
ProteomicsDeciphering the clinical significance and kinase functions of GSK3α in colon cancer by proteomics and phosphoproteomics
In this study, paired tumors and distant normal tissues (DNTs) collected from 78 treatment-naïve colon cancer patients were subjected to tandem mass tag (TMT)-based proteomics. We found that the expression of GSK3α, but not GSK3β, was significantly correlated with the overall survival (OS) of colon ...
ORGANISM(S): Homo Sapiens 
2023-03-03 | PXD038830 |
ProteomicsMagnesium deficiency accelerates gut aging and increases susceptibility to colitis
Metabolic imbalance drives organ aging and diseases, but the underlying mechanisms remain elusive. Here, we identify magnesium (Mg) deficiency as is a risk factor of gut health with age across species (human, primate, murine). Although Mg restriction had minimal effects in young mice, it exacerbated...
ORGANISM(S): Macaca Fascicularis Fascicularis Mus Musculus 
PXD067494 |
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