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UnknownGenome-wide investigation of the AP2/ERF superfamily and their expression under salt stress in Chinese willow (Salix matsudana).
AP2/ERF transcription factors (TFs) play indispensable roles in plant growth, development, and especially in various abiotic stresses responses. The AP2/ERF TF family has been discovered and classified in more than 50 species. However, little is known about the AP2/ERF gene family of Chinese ...
S-EPMC8051338 | biostudies-literature
UnknownPrevalence of posttraumatic stress disorder after infectious disease pandemics in the twenty-first century, including COVID-19: a meta-analysis and systematic review.
Pandemics have become more frequent and more complex during the twenty-first century. Posttraumatic stress disorder (PTSD) following pandemics is a significant public health concern. We sought to provide a reliable estimate of the worldwide prevalence of PTSD after large-scale pandemics as well as a...
S-EPMC7861006 | biostudies-literature
UnknownA systematic review and meta-analysis on the prevalence of stigma in infectious diseases, including COVID-19: a call to action.
Infectious diseases, including COVID-19, are crucial public health issues and may lead to considerable fear among the general public and stigmatization of, and discrimination against, specific populations. This meta-analysis aimed to estimate the pooled prevalence of stigma in infectious disease epi...
S-EPMC8475479 | biostudies-literature
UnknownEfficacy and practice of facemask use in general population: a systematic review and meta-analysis.
In recent decades, respiratory infections, including SARS, HINI and the currently spreading COVID-19, caused by various viruses such as influenza and coronavirus have seriously threatened human health. It has generated inconsistent recommendations on the mandatory use of facemasks across countries o...
S-EPMC8804079 | biostudies-literature
UnknownA systematic review and meta-analysis on prevalence of and risk factors associated with depression, anxiety and insomnia in infectious diseases, including COVID-19: a call to action.
Infectious disease epidemics have become more frequent and more complex during the 21st century, posing a health threat to the general public and leading to psychological symptoms. The current study was designed to investigate the prevalence of and risk factors associated with depression,...
S-EPMC9168354 | biostudies-literature
ProteomicsTargeting tRNA-dependent tyrosine usage unveils a metabolic vulnerability in hepatocellular carcinoma
proteomics and metabolomics analysis of HCC cells cultured in tyrosine deprived medium
ORGANISM(S): Homo Sapiens 
2025-12-30 | PXD072551 |
UnknownGenome-Wide Association Analysis of Protein-Coding Variants in IgA Nephropathy.

Significance statement

Genome-wide association studies have identified nearly 20 IgA nephropathy susceptibility loci. However, most nonsynonymous coding variants, particularly ones that occur rarely or at a low frequency, have not been well investigated. The authors performed a chip-based as...
S-EPMC10631603 | biostudies-literature
UnknownLongitudinal Body Composition Identifies Hepatocellular Carcinoma With Cachexia Following Combined Immunotherapy and Target Therapy (CHANCE2213).

Background

Cancer cachexia can impact prognosis, cause resistance to anticancer treatments and affect the tolerability of treatments. This study aims to identify hepatocellular carcinoma (HCC) with cachexia by characterizing longitudinal body composition (BC) trajectories.

Methods

Thi...
S-EPMC11634469 | biostudies-literature
UnknownImmune checkpoint inhibitors and anti-vascular endothelial growth factor antibody/tyrosine kinase inhibitors with or without transarterial chemoembolization as first-line treatment for advanced hepatocellular carcinoma (CHANCE2201): a target trial emulation study.

Background

The role of transarterial chemoembolization (TACE) in the treatment of advanced hepatocellular carcinoma (HCC) is unconfirmed. This study aimed to assess the efficacy and safety of immune checkpoint inhibitors (ICIs) plus anti-vascular endothelial growth factor (anti-VEGF) antibod...
S-EPMC11090892 | biostudies-literature
UnknownTransarterial chemoembolization with PD-(L)1 inhibitors plus molecular targeted therapies for hepatocellular carcinoma (CHANCE001).
There is considerable potential for integrating transarterial chemoembolization (TACE), programmed death-(ligand)1 (PD-[L]1) inhibitors, and molecular targeted treatments (MTT) in hepatocellular carcinoma (HCC). It is necessary to investigate the therapeutic efficacy and safety of TACE combined with...
S-EPMC9905571 | biostudies-literature
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