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MetabolomicsSalmonella Typhimurium reprograms macrophage metabolism via T3SS effector SopE2 to promote intracellular replication and virulence

Salmonella Typhimurium establishes systemic infection by replicating in host macrophages. Here we show that macrophages infected with S. Typhimurium exhibit upregulated glycolysis and decreased serine synthesis, leading to accumulation of glycolytic intermediates. The effects on...

2024-05-22 | MTBLS2347 | MetaboLights
UnknownGenomic variants of genes associated with three horticultural traits in apple revealed by genome re-sequencing.
Not available
S-EPMC4596325 | biostudies-literature
UnknownlncRNA TRMP-S directs dual mechanisms to regulate p27-mediated cellular senescence.
Not available
S-EPMC8141606 | biostudies-literature
UnknownCan central venous pressure help identify acute right ventricular dysfunction in mechanically ventilated critically ill patients?
Not available
S-EPMC11264666 | biostudies-literature
ProteomicsLC-MS/MS of YfiD-interacting proteins in mammalian cells
To figure out the intracellular function of YfiD, HA-tagged YfiD or Mock was expressed in the HeLa cell line. Subsequently, the lysates of HeLa-YfiD or HeLa-Mock cells were immunoprecipitated with anti-HA beads followed by LC-MS/MS analysis.
ORGANISM(S): Homo sapiens (Human) 
2024-01-15 | PXD047656 | Pride
Lc-ms/ms Yfid Mammalian cells 
ProteomicsLC-MS/MS of an unidentified extracellular protein of Edwardsiella piscicida
This assay aims to identify the composition of an unidentified protein band (~10 kDa) in Edwardsiella piscicida’s extracellular proteins (ECPs). To make this end, this protein band was cut, followed by gel band excision and LC-MS/MS identification.
ORGANISM(S): Edwardsiella tarda EIB202 
2024-01-15 | PXD048313 | Pride
Lc-ms/ms Extracellular protein Edwardsiella piscicida 
ProteomicsESRRB Facilitates the Conversion of Trophoblast-like Stem Cells from Induced Pluripotent Stem cells by Directly Regulating KRT8 and CDX2
Porcine induced pluripotent stem cells (piPSCs) could serve as a great model system for human stem cell pre-clinical research. However, the pluripotency gene network of piPSCs, especially the function for the core transcription factor ESRRB, was poorly understood. Here, we constructed ESRRB-overexpr...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-17 | PXD027539 | Pride
Trophoblast stem cells (tscs) Esrrb Induced pluripotent stem cells (ipscs) Cdx2 Krt8 
ProteomicsLD PROTEOMICS WITH TURBOT INFECTED BY EIB202
To investigate the impact of pathogenic immune stimulation on the lipid droplet (LD) proteome of turbot (Scophthalmus maximus), turbot were intraperitoneally injected with PBS (XA01292LQ_P), wild-type Edwardsiella piscicida EIB202 (XA01292LQ_W), or inactivated E. piscicida EIB202 (XA01292LQ_T). Live...
ORGANISM(S): Scophthalmus maximus 
2024-11-21 | PXD047605 | Pride
Ld 
ProteomicsH-NS LC-MS/MS of Edwardsiella piscicida
This study aims to investigate lysine acetylation sites on the H-NS protein in Edwardsiella piscicida. The H-NS protein was first purified, then subjected to SDS-PAGE, followed by gel band excision and LC-MS/MS identification.
ORGANISM(S): Edwardsiella tarda EIB202 
2024-05-24 | PXD047152 | Pride
Edwardsiella piscicida H-ns Lc-ms/ms 
UnknownHMG-box transcription factor 1: a positive regulator of the G1/S transition through the Cyclin-CDK-CDKI molecular network in nasopharyngeal carcinoma.
Not available
S-EPMC5833394 | biostudies-literature
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