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GenomicGlaucoma Exome Sequencing

This is a study of primary open angle glaucoma (POAG) conducted through exome sequencing of cases and comparison of variant frequencies with general population frequencies available in dbGAP and controlled for sequencing platform artifact to minimize false positives.

POAG is an intraocular...

phs000558 | dbGaP
TranscriptomicsNon-steroidal Anti-inflammatory Drugs Decrease E2F1 Expression and Inhibit Cell Growth in Ovarian Cancer Cells
Epidemiological studies have shown that the regular use of non-steroidal anti-inflammatory (NSAIDs) drugs is associated with a reduced risk of various cancers. In addition, in vitro and experiments in mouse models have demonstrated that NSAIDs decrease tumor initiation and/or progression of several ...
ORGANISM(S): Homo sapiens 
2014-06-20 | E-GEOD-45052 | biostudies-arrayexpress
UnknownSMAD4 mutations and cross-talk between TGF-β/IFNγ signaling accelerate rates of DNA damage and cellular senescence, resulting in a segmental progeroid syndrome-the Myhre syndrome.
Not available
S-EPMC8190230 | biostudies-literature
UnknownSenescent Mesenchymal Stromal Cells Differentially Alter Adipogenesis in Adipose Tissue, Skeletal Muscle, and Bone Marrow.
Not available
S-EPMC12933227 | biostudies-literature
UnknownSenolytic therapy in mild Alzheimer's disease: a phase 1 feasibility trial.
Not available
S-EPMC10875739 | biostudies-literature
UnknownSenolytics reduce coronavirus-related mortality in old mice.
Not available
S-EPMC8607935 | biostudies-literature
TranscriptomicsEffects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Calorie restriction (CR) is the most robust non-genetic intervention to universally delay the onset of age-related diseases and extend mean and maximum lifespan. However, species, strain, sex, diet, age of onset, and level of CR are emerging as important variables to consider for a successful CR res...
ORGANISM(S): Mus musculus 
2016-06-27 | E-GEOD-81959 | biostudies-arrayexpress
UnknownGlobal Retinoblastoma Presentation and Analysis by National Income Level.
Not available
S-EPMC7047856 | biostudies-literature
UnknownHyperoxemia and excess oxygen use in early acute respiratory distress syndrome: insights from the LUNG SAFE study.
Not available
S-EPMC7110678 | biostudies-literature
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