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We generated gene expression profiles from 498 primary neuroblastomas using RNA-Seq and microarrays. We sought to systematically evaluate the capability of RNA deep-sequencing (RNA-Seq)-based classification for clinical endpoint prediction in comparison to microarray-based ones. The neuroblastoma co...
ORGANISM(S): Homo sapiens 
Nuclear extracts were isolated from 293T cells that stably express USP44 fused with N-terminal FLAG and HA affinity tags (FH-USP44), and then analyzed by tandem affinity purification (TAP) followed by Multidimensional Protein Identification Technology (MudPIT) to uncover USP44 associated proteins. T...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
Background: Metabolic dysfunction–associated steatotic liver disease (MASLD) progresses from simple steatosis to metabolic dysfunction–associated steatohepatitis (MASH), yet its therapeutic development has been hampered by pathological complexity and heterogeneity. Methods: Bulk RNA-seq and diet-in...
ORGANISM(S): Mus Musculus 
This project presents the proteomic profiling of protein complexes associated with the transcription factor TCF21, achieved through affinity purification coupled with mass spectrometry (AP-MS). The study aimed to comprehensively map the TCF21 interactome in two distinct cellular models: the human co...
ORGANISM(S): Homo Sapiens 
2025-12-12 | PXD071976 |
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