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GenomicsSingle Cell Sequencing Identifies Key Epigenetic Regulators in Nuclear Transfer Mediated Reprogramming [RRBS]
Differentiated cell can be reprogrammed into totipotent embryo through somatic cell nuclear transfer (SCNT). However, this process is highly inefficient and most cloned embryos arrest at certain developmental stages. Through single cell sequencing combined with embryo biopsy, here we generate a glob...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-70607 | biostudies-arrayexpress
UnknownA programmable pAgo nuclease with high activity and specificity for efficient DNA and RNA manipulation.
Not available
S-EPMC12657969 | biostudies-literature
GenomicsSingle Cell Sequencing Identifies Key Epigenetic Regulators in Nuclear Transfer Mediated Reprogramming [ChIP-seq]
Differentiated cell can be reprogrammed into totipotent embryo through somatic cell nuclear transfer (SCNT). However, this process is highly inefficient and most cloned embryos arrest at certain developmental stages. Through single cell sequencing combined with embryo biopsy, here we generate a glob...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-70606 | biostudies-arrayexpress
ProteomicsJuvenile hormone membrane signaling phosphorylates Hsp83 and promotes Met nuclear import
JH modulates phosphorylation modification of components of its intracellular signaling through putative membrane pathway. As a transcriptional factor, Met phosphorylation is contributed to its transcriptional activity, but whether phosphorylation modification affects Met nuclear import is unknown. ...
ORGANISM(S): Drosophila Melanogaster 
2021-07-15 | PXD027314 |
ProteomicsProteomic Data of Uterine Tissues from 6 Chickens
The integration of proteomics and metabolomics reveals the differences in the uterine tissues of hens producing normal eggs and pimpled eggs
ORGANISM(S): Gallus Gallus 
2024-11-11 | PXD057730 |
TranscriptomicsTet1 can substitute for pluripotent transcription factors in reprogramming differentiated somatic cells to pluripotency
Ten-eleven translocation (TET) family enzymes can convert 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) in DNA and have been proposed as potential DNA demethylase candidates1. Evidences from recent studies indicated that Tet1 is predominantly expressed in ES cells and plays dual functio...
ORGANISM(S): Mus musculus 
2011-05-07 | E-GEOD-29102 | biostudies-arrayexpress
TranscriptomicsSingle Cell Sequencing Identifies Key Epigenetic Regulators in Nuclear Transfer Mediated Reprogramming [RNA-seq]
Differentiated cell can be reprogrammed into totipotent embryo through somatic cell nuclear transfer (SCNT). However, this process is highly inefficient and most cloned embryos arrest at certain developmental stages. Through single cell sequencing combined with embryo biopsy, here we generate a glob...
ORGANISM(S): Mus musculus 
2016-05-17 | E-GEOD-70605 | biostudies-arrayexpress
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