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The current study provides an opportunity to identify specific MHC I motifs in vitro. The combination of random peptide library, LC-MS/MS and De Novo Sequencing can be an important complement to the identification of MHC I motif. Insight into the length distribution of MHC-I binding peptides helps u...
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2022-02-25 | PXD020818 | Pride
The current study provides an opportunity to identify specific MHC I motifs in vitro.The combination of random peptide library,LC-MS/MS and De Novo Sequencing can be an important complement to the identification of MHC I motif.
ORGANISM(S): Sus scrofa domesticus (domestic pig) 
2021-09-09 | PXD019523 | Pride
Mouse Marginal Zone B-cell with/without Tfh
ORGANISM(S): Mus musculus 
Despite the significance of nucleus genes in plant growth and development, little is known of the molecular bases of regulation of photosynthesis in woody plants.Hence discovering the genetic basis for photosynthesis related phenotypic variation and identifying the major genes controlling these comp...
ORGANISM(S): (Populus alba x Populus glandulosa) x Populus tomentosa 
Pu-erh tea displays cholesterol-lowering properties, but the underlying mechanism has not been elucidated. Theabrownin is one of the most active and abundant pigments in Pu-erh tea. Here, we show that theabrownin alters the gut microbiota in mice and humans, predominantly suppressing microbes associ...
2021-11-18 | MTBLS1259 | MetaboLights
Hyocholic acid (HCA) is a major bile acid (BA) species in the BA pool of pigs, a species known for its exceptional resistance to spontaneous development of diabetic phenotypes. HCA and its derivatives are also present in human blood and urine. We investigate whether human HCA profiles can predict th...
2021-10-06 | MTBLS2343 | MetaboLights

The incidence of intestinal diseases increases with age, but the regulators of gut aging and the molecules linking gut aging and diseases remain largely unknown. By profiling the transcriptome, proteome, phosphoproteome and metabolome of 104 Macaca fascicularis large intestinal tissues, ...

2023-12-14 | MTBLS7612 | MetaboLights
Understanding factors that drive development and function of the sinoatrial node (SAN) is crucial to development of potential therapies for sinus arrhythmias, including potential generation of biological pacemakers. Here, we identify a key cell autonomous role for the LIM homeodomain transcription f...
ORGANISM(S): Mus musculus 
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