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Enhancers, through the combinatorial action of transcription factors (TFs), dictate both the spatial specificity and the levels of gene expression, and their aberrations can result in diseases. While HMX1 downstream enhancer is associated to ear malformations, the mechanisms underlying bilateral con...
ORGANISM(S): Mus musculus (Mouse) 
2025-04-28 | PXD063373 | Pride
To identify asymmetrically localized maternal mRNAs along the animal-vegetal axis in cleavage Xenopus embryos, we isolated animal and vegetal blastomeres at 8-cell stage, extracted the maternal mRNA respectively and analyzed them by RNA-seq technology. We identified 43 maternal transcripts significa...
ORGANISM(S): Xenopus laevis 
Metabolic Reprogramming in Hepatocellular Carcinoma: An Integrated Omics Study of Lipid Pathways and Their Diagnostic Potential
ORGANISM(S): Homo Sapiens 
2025-03-20 | PXD062049 |
Background: Moyamoya disease (MMD) signifies a cerebrovascular disorder with obscure origin and a more rapid and severe progression in children than adults. This investigation aims to uncover age-associated distinctions through proteomic and metabolomic profiling to gain insights into the underlying...
ORGANISM(S): Homo Sapiens 
2025-04-24 | PXD063265 |
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